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Isoaminile
go.drugbank.com/drugs/DB08944ApprovedWithdrawnIsoaminile, an antitussive drug with a structure similar to methadone, is also an anticholinergic with both antimuscarinic and antinicotinic properties.
RESP301
go.drugbank.com/drugs/DB16497InvestigationalIt was studied in community patients at risk of viral infections, including SARS-CoV-2, in a terminated trial (NCT04858451) and adults with rifampicin-susceptible pulmonary tuberculosis in a recruiting … RESP301 was also studied in a terminated trial (NCT05101915) for patients with mycobacterium abscesses and cystic fibrosis and in a completed trial with results (NCT04460183) for efficacy and safety in
Didesmethylrocaglamide
go.drugbank.com/drugs/DB15496Experimental[A186760] While traditionally used for their insecticidal benefits,[A186796] this class of compounds is now being studied for use as chemotherapeutic agents in the treatment of various leukemias, lymphomas
XL784
go.drugbank.com/drugs/DB04991InvestigationalXL784 is a potent inhibitor of the ADAM-10 metalloprotease enzyme, a target of significant interest because of its important role in blood vessel formation and cell proliferation.
Mequitazine
go.drugbank.com/drugs/DB01071InvestigationalIt competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract.
Certoparin
go.drugbank.com/drugs/DB09261ApprovedCertoparin is part of the heparins of low molecular weight that presents high activity against the coagulation factor Xa. It is normally used to prevent deep venous thrombosis.
Polydatin
go.drugbank.com/drugs/DB11263ApprovedIt is shown to mediate a cytotoxic action on colorectal cancer cells by inducing cell arrest and apoptosis [A27229]. … While it is isolated from the bark of *Picea sitchensis* or *Polygonum cuspidatum*, polydatin may be detected in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products
Synonyms: Polydatin (E)-isomerRice bran oil
go.drugbank.com/drugs/DB11293ApprovedInvestigationalRice bran oil is classified as an indirect additive used in food contact substances by the FDA.
Pirlindole
go.drugbank.com/drugs/DB09244ExperimentalIt was developed and is currently used as an antidepressant in Russia. Its chemical structure is similar to metralindole, and it also shares pharmacological properties with this drug. … The antidepressant efficacy and safety of pirlindole have been demonstrated in numerous studies and, supported by many years of clinical experience in the treatment of depression.
Hymecromone
go.drugbank.com/drugs/DB07118InvestigationalCategories: Compounds used in a research, industrial, or household setting