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Displaying results 4621 - 4630 of 10000 in total
  1. Drug

    Omburtamab

    go.drugbank.com/drugs/DB15635
    Investigational

    [A191829] Omburtamab is under investigation in clinical trial NCT03275402 (131i-omburtamab Radioimmunotherapy for Neuroblastoma Central Nervous System/leptomeningeal Metastases). … [A242487, A242492] Omburtamab, formerly the murine anti-B7-H3 antibody 8H9, and its humanized forms are currently under clinical development for use in various cancers.

  2. Drug

    QS-21

    go.drugbank.com/drugs/DB05400
    Investigational

    It is the leading member of the Stimulon family of adjuvants. As a vaccine additive, it is currently being evaluated in clinical trials in a variety of disease areas by Antigenics. … QS-21 is an investigational adjuvant, which is a substance added to vaccines and other immunotherapies that is designed to enhance the body’s immune response to the antigen contained within the treatment

  3. Drug

    Bucillamine

    go.drugbank.com/drugs/DB12160
    Investigational

    Bucillamine has been used in trials studying the treatment and prevention of Gout and Rheumatoid Arthritis.

    Categories: Compounds used in a research, industrial, or household setting
  4. Drug

    EHC18

    go.drugbank.com/drugs/DB05114
    Experimental

    EHC18 is an immune regulation medicine. It is a broad spectrum of specific HCV proteins.

  5. Drug

    Pirlindole

    go.drugbank.com/drugs/DB09244
    Experimental

    Pirlindole is a selective, reversible inhibitor of monoamine oxidase (MAO) subtype A (MAO-A) that is approved in several European and non-European countries for the treatment of major depression. … This drug is classified as a reversible inhibitor of monoamine oxidase A enzyme (also known as a RIMA drug). It was developed and is currently used as an antidepressant in Russia.

  6. Drug

    Docosanol

    go.drugbank.com/drugs/DB00632
    Approved

    Docosanol is a drug used for topical treatment for recurrent herpes simplex labialis episodes (episodes of cold sores or fever blisters).

    Synonyms: N-Docosanol
  7. Drug

    Uracil mustard

    go.drugbank.com/drugs/DB00791
    Approved

    It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal and bone marrow damage.

    Synonyms: 5-N,N-bis(2-chloroethyl)aminouracil
  8. Drug

    Iclaprim

    go.drugbank.com/drugs/DB06358
    Investigational

  9. Drug

    Ximelagatran

    go.drugbank.com/drugs/DB04898
    ApprovedWithdrawn

    In 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and to discontinue its distribution in countries … Ximelagatran is an anticoagulant intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and monitoring issues associated with the former.

    Synonyms: ethyl 2-[[(1R)-1-cyclohexyl-2- [(2S)-2-[[4-(N'-hydroxycarbamimidoyl) phenyl]methylcarbamoyl]azetidin-1-yl]- 2-oxo-ethyl]amino]acetate
  10. Drug

    Aluminum oxide

    go.drugbank.com/drugs/DB11342
    ApprovedWithdrawn

    It is amphoteric in nature, and is used in various chemical, industrial and commercial applications. It is considered an indirect additive used in food contact substances by the FDA.