Aluminum oxide

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Aluminum oxide
DrugBank Accession Number
DB11342
Background

Aluminum oxide has a chemical formula Al2O3. It is amphoteric in nature, and is used in various chemical, industrial and commercial applications. It is considered an indirect additive used in food contact substances by the FDA.

Type
Small Molecule
Groups
Approved
Structure
Thumb
Weight
Average: 101.96
Monoisotopic: 101.9478209
Chemical Formula
Al2O3
Synonyms
  • Aluminium oxide

Pharmacology

Indication

Not Available

Pharmacology
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Associated Conditions
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
CarbamazepineAluminum oxide can cause a decrease in the absorption of Carbamazepine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Chenodeoxycholic acidAluminum oxide can cause a decrease in the absorption of Chenodeoxycholic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
Cholic AcidAluminum oxide can cause a decrease in the absorption of Cholic Acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
DeferasiroxAluminum oxide can cause a decrease in the absorption of Deferasirox resulting in a reduced serum concentration and potentially a decrease in efficacy.
Dehydrocholic acidAluminum oxide can cause a decrease in the absorption of Dehydrocholic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
Deoxycholic acidAluminum oxide can cause a decrease in the absorption of Deoxycholic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
DolutegravirThe serum concentration of Dolutegravir can be decreased when it is combined with Aluminum oxide.
EltrombopagAluminum oxide can cause a decrease in the absorption of Eltrombopag resulting in a reduced serum concentration and potentially a decrease in efficacy.
HalofantrineAluminum oxide can cause a decrease in the absorption of Halofantrine resulting in a reduced serum concentration and potentially a decrease in efficacy.
MephenytoinAluminum oxide can cause a decrease in the absorption of Mephenytoin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Interactions
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Food Interactions
No interactions found.

Products

Products2
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Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
ALUMINIUM HYDROXIDE MIXTURE BP 4% w/wSuspension4 % w/wOralSUNWARD PHARMACEUTICAL PRIVATE LIMITED1989-04-21Not applicable
ALUTACID ANTACID MIXTURE 4% w/wSuspension4 % w/wOralICM PHARMA PTE. LTD.1996-07-03Not applicable
Brasivol FineCream38.2 %TopicalStiefel Laboratories, Inc.1966-12-312000-01-07Canada flag
Brasivol MediumCream52.2 %TopicalStiefel Laboratories, Inc.1966-12-312000-01-07Canada flag
Vfb Bio PeelPowder6.5 mg/1gTopicalGeneral Bio Co., Ltd.2014-12-092019-09-30US flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
POLGENTEC 2-120 GBQ GENERADOR DE RADIONUCLEIDOSAluminum oxide (2 g) + Sodium molybdate (0 GBq) + Technetium Tc-99m sodium pertechnetate (120 GBq)SolutionIntravenousISOMEDIX TECHNOLOGY S.A.S.2013-09-19Not applicableColombia flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Vfb Bio PeelAluminum oxide (6.5 mg/1g)PowderTopicalGeneral Bio Co., Ltd.2014-12-092019-09-30US flag

Categories

ATC Codes
D10AX04 — Aluminium oxide
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of inorganic compounds known as post-transition metal salts. These are inorganic halogenic compounds in which the heaviest metal atom is a post-transition metal.
Kingdom
Inorganic compounds
Super Class
Mixed metal/non-metal compounds
Class
Post-transition metal salts
Sub Class
Not Available
Direct Parent
Post-transition metal salts
Alternative Parents
Miscellaneous mixed metal/non-metals / Inorganic salts
Substituents
Inorganic post-transition metal salt / Inorganic salt / Miscellaneous mixed metal/non-metal
Molecular Framework
Not Available
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
LMI26O6933
CAS number
1344-28-1
InChI Key
PNEYBMLMFCGWSK-UHFFFAOYSA-N
InChI
InChI=1S/2Al.3O/q2*+3;3*-2
IUPAC Name
dialuminium(3+) ion trioxidandiide
SMILES
[O--].[O--].[O--].[Al+3].[Al+3]

References

General References
Not Available
PubChem Compound
9989226
PubChem Substance
347827970
ChemSpider
8164808
RxNav
615
ChEMBL
CHEMBL3707210
Wikipedia
Aluminium_oxide

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SuspensionOral4 % w/w
CreamTopical38.2 %
CreamTopical52.2 %
SolutionIntravenous
PowderTopical6.5 mg/1g
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP-0.65ChemAxon
pKa (Strongest Acidic)15.7ChemAxon
pKa (Strongest Basic)-1.8ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count1ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity13.11 m3·mol-1ChemAxon
Polarizability0.95 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Drug created on December 03, 2015 16:52 / Updated on May 21, 2021 10:22