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Displaying results 4631 - 4640 of 10000 in total
  1. Drug

    Ispectamab debotansine

    go.drugbank.com/drugs/DB18456
    Investigational

    Ispectamab debotansine is an antibody drug conjugate comprised of an anti-B cell maturation (BCMA) IgG1 humanized antibody conjugated covalently to the dibenzocyclooctyne (DBCO) noncleavable linker maytansinoid

  2. Drug

    LMB-100

    go.drugbank.com/drugs/DB18591
    Investigational

    LMB-100 is a is an antibody-toxin conjugate with an antimesothelin Fab linked to a 24-kilodalton portion of Pseudomonas exotoxin A with mutations that decrease immunogenicity.

  3. Drug

    Distigmine

    go.drugbank.com/drugs/DB13694
    Investigational

    Distigmine is a parasympathomimetic agent with a longer duration of action and enhanced drug accumulation compared to [DB00545] and [DB01400]. … Distigmine is available in several countries as a treatment of underactive detrusor and voiding dysfunction in the urinary tract where the active ingredient is distigmine bromide.

  4. Drug

    Covid-19 Coronavirus Artificial Antigen Presenting Cell Vaccine

    go.drugbank.com/drugs/DB15813
    Investigational

    Through analysis of potential immunogenic targets of the SARS-Cov2 genome, a synthetic ‘minigene’ was developed using domains of viral structural proteins and a polyprotein protease. … As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials.

  5. Drug

    Chlormadinone acetate

    go.drugbank.com/drugs/DB15903
    ApprovedWithdrawn

    In the US, chlormadinone acetate was formerly marketed as a component of the combination drug products Estalor-21 and C-Quens. … Chlormadinone acetate is a progesterone derivative first synthesized in 1961.

  6. Drug

    Nilutamide

    go.drugbank.com/drugs/DB00665
    ApprovedInvestigational

    Nilutamide is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer. … Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors (but not for progestogen, estrogen, or glucocorticoid receptors).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 Inhibitors
  7. Drug

    Benzyl benzoate

    go.drugbank.com/drugs/DB00676
    Approved

    Scabies is a skin infection caused by the mite sarcoptes scabiei. It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection.

    Categories: Compounds used in a research, industrial, or household settingProducts: BENZYL BENZOATE APPLICATION BP 25% w/v
  8. Drug

    Butylscopolamine

    go.drugbank.com/drugs/DB09300
    ApprovedInvestigationalVet approved

    It is also effective at preventing bladder spasms. … Butylscopolamine is a peripherally acting antimuscarinic, anticholinergic agent.

    Products: HİYOSPAZM 20 MG/ML İM/İV/SC ENJEKSİYONLUK ÇÖZELTİ, GİBURİN 20 MG/ML IM/IV/SC ENJEKSİYONLUK ÇÖZELTİ, 6 ADET
  9. Drug

    Caficrestat

    go.drugbank.com/drugs/DB15121
    Investigational

    AT-001 is under investigation in clinical trial NCT03062384 (AT-001 for Long-term Preservation of Brain Health in Aging).

  10. Drug

    N-Formylmethionine

    go.drugbank.com/drugs/DB04464
    Experimental

    The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA. This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eucaryotic cells.