DB00676ApprovedSmall molecule
Benzyl benzoate is a topical treatment for scabies and lice. Scabies is a skin infection caused by the mite sarcoptes scabiei.
- Mechanism
- Curator reviewed
Benzyl benzoate exerts toxic effects on the nervous system of the parasite, resulting in its death. It is also toxic to mite ova, though its exact mechanism of action is unknown. In vitro, benzyl benzoate has been found to kill the Sarcoptes mite within 5 minutes.
- Primary indication
- Used to kill lice and the mites responsible for the skin condition scabies.Curator reviewed · 2 structured indications
- Formula / weight
- C14H12O2 · 212.2439 g/mol (avg)
- Also known as
- Acarobenzyl · Benylate · Benzevan · Benzoic acid phenylmethylester · Phenylmethyl benzoate
- Code names
- FEMA NO. 2138 · NSC-8081
Resolves to
Clinical / RWD
Structure
InChIKey
SESFRYSPDFLNCH-UHFFFAOYSA-NSMILESO=C(OCC1=CC=CC=C1)C1=CC=CC=C1Targets
What you can answer from here — as of August 31, 2026
1Protein targetEach mapped to UniProt, with action and pharmacological actionListed above
Which drugs share a target with Benzyl benzoate, and which of those have an active Phase 3 trial?
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