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BOS172722
go.drugbank.com/drugs/DB15498InvestigationalThe key role of Mps1 in the growth of cancer cells renders it an appealing target for cancer treatment, as its inhibition could lead to favorable effects. … [A187120] An in vivo study combined BOS172722 with [Paclitaxel] for the treatment of triple hormone receptor negative breast cancer, and demonstrated promising synergistic effects.[A187123]
Monensin
go.drugbank.com/drugs/DB11430ExperimentalVet approvedIt is widely used in ruminant animal feeds.
Categories: Compounds used in a research, industrial, or household settingCholic Acid
go.drugbank.com/drugs/DB02659ApprovedInvestigationalA major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.
VIT-100
go.drugbank.com/drugs/DB05865ExperimentalIn preclinical studies, companyl has shown that VIT-100 inhibits the growth of cells taken from multiple keloid biopsies as compared to the same keloidal cells treated with a control. … It is believed that similar effects would be seen in cells isolated from hypertrophic scars.
Peptide YY (3-36)
go.drugbank.com/drugs/DB05004InvestigationalIt reduces appetite and increases satiety in obese patients.
SO-101
go.drugbank.com/drugs/DB05345ExperimentalSO-101(Silenor) is a low-dose oral tablet formulation of doxepin hydrochloride that is patent protected for its use in insomnia.
BLX-883
go.drugbank.com/drugs/DB05904InvestigationalAlfa interferon is used in the treatment of hepatitis C, hepatitis B, and multiple cancers and its worldwide sales currently exceed $3 billion.
ISS-1018
go.drugbank.com/drugs/DB05463InvestigationalISS 1018 is currently being investigated in combination with HBsAg vaccine as a prophylactic treatment for to prevent Hepatitis B in adults. … It is also being investigated in combination with rituximab for treatment of b-cell or non-hodgkin's lymphoma.
XL844
go.drugbank.com/drugs/DB05149InvestigationalXL844 is a potent inhibitor of the checkpoint kinases CHK1 and CHK2, which induce cell cycle arrest in response to a variety of DNA damaging agents.
Acifluorfen
go.drugbank.com/drugs/DB07338ExperimentalAcifluorfen is a protoporphyrinogen oxidase inhibitor.
Categories: Compounds used in a research, industrial, or household setting