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Oral Polio Vaccine
go.drugbank.com/drugs/DB15864InvestigationalStrains of the virus are selected based on their reduced incidence of spreading to the central nervous system but still having the ability to mimic the immune response that occurs after infection with … The vaccine is created by weakening the wildtype before being placed into the oral vaccine.
Sitaxentan
go.drugbank.com/drugs/DB06268ApprovedWithdrawnSitaxentan was marketed under the trade name Thelin for the treatment of pulmonary arterial hypertension (PAH) by Encysive Pharmaceuticals until Pfizer purchased Encysive in February 2008. … In 2010, Pfizer voluntarily removed sitaxentan from the market over concerns of hepatotoxicity.
Categories: Endothelin Receptor AntagonistsINZ-701
go.drugbank.com/drugs/DB17629InvestigationalINZ-701 is an enzyme replacement therapy under development with the intention to be used for the treatment of calcification disorders of the circulatory system, bones, and kidneys.
Synonyms: Recombinant human ectonucleotide pyrophosphatase/phosphodiesterase 1 fused to the Fc fragment of IGG1 (INZ-701)Radotinib
go.drugbank.com/drugs/DB12323InvestigationalRadotinib is under investigation for the treatment of Leukemia, Myelogenous, Chronic, BCR-ABL Positive.
Propacetamol
go.drugbank.com/drugs/DB09288InvestigationalPropacetamol is a non-opioid analgesic devoid of the major contraindications. … Propacetamol is a parenteral formulation of paracetamol and thus, it is a prodrug that is completely hydrolyzed to paracetamol.
Temanogrel
go.drugbank.com/drugs/DB05227InvestigationalAPD791 is intended to lower the risk of arterial thrombosis by reducing the amplification of platelet aggregation, arterial constriction and intimal hyperplasia mediated by serotonin.
Categories: Serotonin Receptor Antagonists, Serotonin 5-HT2 Receptor AntagonistsAtipamezole
go.drugbank.com/drugs/DB11481InvestigationalVet approvedAtipamezole is a synthetic α2 adrenoceptor antagonistused to reverse the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs.
Categories: Adrenergic alpha-2 Receptor AntagonistsMethallenestril
go.drugbank.com/drugs/DB13143ExperimentalCategories: Sex Hormones and Modulators of the Genital SystemMethylestrenolone
go.drugbank.com/drugs/DB13533InvestigationalCategories: Sex Hormones and Modulators of the Genital SystemDihydroxymethoxychalcone
go.drugbank.com/drugs/DB14122Investigationalto human health. … Cardamonin (also known as Dihydroxymethoxychalcone), as shown by the increasing number of publications, has received growing attention from the scientific community due to the expectations toward its benefits
Synonyms: (E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one