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Displaying results 4661 - 4670 of 5504 in total
  1. Drug

    Human umbilical cord blood mononuclear cell-conditioned medium

    go.drugbank.com/drugs/DB15724
    Experimental

    Transplantation with human umbilical cord blood mononuclear cells (HUCBC) has demonstrated promising results in various disease states. While some of the positive results are credited to HUCBCs’ differentiation potential, the growth fact...

  2. Drug

    KAND567

    go.drugbank.com/drugs/DB16511
    Investigational

    KAND567, a small molecule, blocks the fractaline (CX3CL1) receptor, which mediates the immune system response to inflammation . Because COVID-19 involves cytotoxic cells associated with this pathway, KAND567 is currently being tested as ...

  3. Drug

    OXI-4503

    go.drugbank.com/drugs/DB05143
    Investigational

    OXI-4503 is investigated in clinical trials for treating cancer/tumors. OXI-4503 is a solid. OXI-4503 blocks and destroys tumor vasculature, resulting in extensive tumor cell death and necrosis. OXI-4503 (combretastatin A1 di-phosphate /...

  4. Drug

    Delandistrogene moxeparvovec

    go.drugbank.com/drugs/DB16802
    ApprovedInvestigational

    It was granted accelerated approval by the FDA on June 22, 2023, as the first gene therapy to treat Duchenne Muscular Dystrophy (DMD).

  5. Drug

    Tabelecleucel

    go.drugbank.com/drugs/DB17072
    ApprovedInvestigational

    It is produced by mixing T-cells with B-cells that have been infected with the Epstein-Barr virus (EBV). … Both T-cells and B-cells are obtained from the same donor, and T-cells are grown to increase their numbers.

  6. Drug

    Oveporexton

    go.drugbank.com/drugs/DB21680
    Approved

    [L64068,L64069] It is the first orexin receptor agonist approved by the FDA and the first medicine to treat NT1 by targeting its underlying cause rather than individual symptoms.

  7. Drug

    CGC-11047

    go.drugbank.com/drugs/DB05722
    Investigational

    CGC-11047 is a polyamine analog designed to halt cell growth and induce apoptosis.

  8. Drug

    Dacetuzumab

    go.drugbank.com/drugs/DB12589
    Investigational

    It is a humanized anti-CD40 antibody and induces cytotoxicity in human multiple myeloma cells.

  9. Drug

    Magnesium aspartate

    go.drugbank.com/drugs/DB13359
    Investigational

    It displays high oral bioavailability and water solubiltiy compared to other magnesium salts such as magnesium citrate, magnesium carbonate and magnesium oxide.

  10. Drug

    5-imino-4-(3-trifluoromethyl-phenylazo)-5H-pyrazol-3-ylamine

    go.drugbank.com/drugs/DB08666
    Experimental

    These are aromatic compounds containing at least one benzene ring. This drug targets the protein methionine aminopeptidase.