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Displaying results 4681 - 4690 of 5896 in total
  1. Drug

    Dirocaftor

    go.drugbank.com/drugs/DB16143
    Investigational

    Dirocaftor is under investigation in clinical trial NCT03251092 (Study Designed to Assess the Safety, Tolerability and PK of PTI-808 in Healthy Volunteers and in Adults With Cystic Fibrosis).

  2. Drug

    AIM-102

    go.drugbank.com/drugs/DB16176
    Investigational

    AIM-102 is under investigation in clinical trial NCT01501942 (Efficacy, Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of Oral Administration of AIM-102 in Patients With Mild to Moderate Allergic

  3. Drug

    Revaprazan

    go.drugbank.com/drugs/DB16308
    Investigational

    Revaprazan is under investigation in clinical trial NCT01750437 (Phase 2 Clinical Trial to Investigate the Safety, Tolerability and Efficacy of YH1885L in Patients With Non-erosive Reflux Disease(nerd)

  4. Drug

    HTPEP-001

    go.drugbank.com/drugs/DB18730
    Experimental

    HTPEP-001 is a novel peptide that works to inhibit the activation of transforming growth factor beta (TGF-β). It is being investigated for the treatment of fibrosis.[A263527]

  5. Drug

    Deutarserine

    go.drugbank.com/drugs/DB19057
    Investigational

    Deutarserine is under investigation in clinical trial NCT04158687 (A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-692 as an Adjunctive Treatment in Adults With Schizophrenia).

  6. Drug

    Pacibekitug

    go.drugbank.com/drugs/DB19307
    Investigational

    Human anti-il-6 monoclonal antibody (pf-04236921) is under investigation in clinical trial NCT01405196 (Subcutaneous Treatment in Randomized Subjects to Evaluate Safety and Efficacy in Generalized Lupus

  7. Drug

    PF-06291874

    go.drugbank.com/drugs/DB15065
    Investigational

    PF-06291874 is under investigation in clinical trial NCT02175121 (Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Study of PF-06291874 as Oral Monotherapy To Treat Adults With Type 2 Diabetes

  8. Drug

    Urolithin A

    go.drugbank.com/drugs/DB15464
    Experimental

    It has been demonstrated to stimulate mitophagy and improve muscle health in old animals and in preclinical models of aging.[A179494]

  9. Drug

    Linifanib

    go.drugbank.com/drugs/DB06080
    Investigational

    Linifanib (ABT-869) is a small molecule vascular endothelial growth factor (VEGF) receptor-based kinase inhibitor that is designed to suppress tumor growth by preventing the formation of new blood vessels

  10. Drug

    H3B-8800

    go.drugbank.com/drugs/DB14017
    Investigational

    It offers the benefit of preferentially killing spliceosome-mutant cancer cells whereas other splicesome inhibitors, such as the pladienolide analogue E7107, show no such preferential targeting [A32749