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Displaying results 461 - 470 of 10000 in total
  1. Drug

    Delamanid

    go.drugbank.com/drugs/DB11637
    ApprovedInvestigational

    Multidrug-resistant tuberculosis may also require more than 2 years of chemotherapy and second-line therapies with narrow therapeutic index [A31968]. … It is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in a combination regimen.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: (2R)-2-methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)methyl)-2,3-dihydroimidazo(2,1-B)(1,3)oxazole, (R)-2-methyl-6-nitro-2-{4-[4-(4-trifluoromethoxyphenoxy)piperidin-1-yl]phenoxymethyl}-2,3-dihydroimidazo[2,1-b]oxazole
  2. Drug

    4-(4-FLUOROBENZYL)PIPERIDINE

    go.drugbank.com/drugs/DB07110
    Experimental

    Synonyms: 4-(4-FLUOROBENZYL)PIPERIDINE
  3. Drug

    4-(4-Chlorophenyl)Imidazole

    go.drugbank.com/drugs/DB02974
    Experimental

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-(4-Chlorophenyl)Imidazole
  4. Drug

    Cholesteryl Linoleate

    go.drugbank.com/drugs/DB02092
    Experimental

    Synonyms: (3β)-cholest-5-en-3-ol, (Z,Z)-9,12-octadecadienoate, (Z,Z)-(3beta)-Cholest-5-en-3-ol 9,12-octadecadienoate
  5. Drug

    Dapsone

    go.drugbank.com/drugs/DB00250
    ApprovedInvestigational

    A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. … It is also used with pyrimethamine in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)

    Mixtures: Dapsone 6% / Niacinamide 4%, Dapsone 8.5% / Niacinamide 4%Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Inducers
  6. Drug

    Fentanyl

    go.drugbank.com/drugs/DB00813
    ApprovedIllicitInvestigationalVet approved

    Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. … Fentanyl's high potency has also made it a common adulterant in illicit drugs, especially heroin.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: N-(1-phenethyl-4-piperidinyl)-N-phenylpropionamide, N-phenethyl-4-(N-propionylanilino)piperidine
  7. Drug

    (1Z)-2-HYDROXY-3-OXOHEX-1-EN-1-YL DIHYDROGEN PHOSPHATE

    go.drugbank.com/drugs/DB06881
    Experimental

    Synonyms: (1Z)-2-HYDROXY-3-OXOHEX-1-EN-1-YL DIHYDROGEN PHOSPHATE
  8. Drug

    4-{[5-(CYCLOHEXYLAMINO)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE

    go.drugbank.com/drugs/DB07686
    Experimental

    Synonyms: 4-{[5-(CYCLOHEXYLAMINO)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE
  9. Drug

    4-{[5-(CYCLOHEXYLOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE

    go.drugbank.com/drugs/DB07688
    Experimental

    Synonyms: 4-{[5-(CYCLOHEXYLOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE
  10. Drug

    Amsacrine

    go.drugbank.com/drugs/DB00276
    ApprovedInvestigationalWithdrawn

    Aminoacridine derivative that is a potent intercalating antineoplastic agent. … It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors.

    Categories: Compounds used in a research, industrial, or household setting, P-glycoprotein inhibitorsSynonyms: 4'-(9-Acridinylamino)methanesulfon-m-anisidide, 4'-(9-Acridinylamino)methanesulphon-m-anisidide