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Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
go.drugbank.com/bio_entities/BE0001080TargetHumansGuanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems (PubMed:29925951, PubMed:33762731, PubMed:34239069, PubMed:35610220, PubMed:35714614, PubMed:35835867, ...
Polypeptides: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2Synonyms: G gamma-INateglinide
go.drugbank.com/drugs/DB00731ApprovedThe average weight gain caused by meglitinides appears to be lower than that caused by sulfonylureas and insulin and appears to occur only in those naïve to oral antidiabetic agents. … It belongs to the meglitinide class of short-acting insulin secretagogues, which act by binding to β cells of the pancreas to stimulate insulin release.
Categories: Drugs Used in Diabetes, Cytochrome P-450 SubstratesProducts: STARLIX 60 MG COMPRIMIDOS CON CUBIERTA PELICULAR, STARLIX 120 MG COMPRIMIDOS CON CUBIERTA PELICULARPralatrexate
go.drugbank.com/drugs/DB06813ApprovedInvestigational[A246693] Pralatrexate is designed to have a higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and is upregulated by oncogenes. … [A246703] Pralatrexate was approved by the FDA on September 24, 2009.
Categories: Heterocyclic Compounds, 2-RingSynonyms: (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid, N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acidEstramustine
go.drugbank.com/drugs/DB01196ApprovedWithdrawnA nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsSynonyms: Estradiol 3-(N,N-bis(2-chloroethyl)carbamate), 17β-Estradiol 3-(bis(2-chloroethyl)carbamate)Ketoprofen
go.drugbank.com/drugs/DB01009ApprovedInvestigationalVet approvedKetoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Mixtures: VOTRIPAX-KNO, BI-PROFENIDCategories: Non COX-2 selective NSAIDS, Anti-Inflammatory Agents, Non-Steroidal (Non-Selective)(3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiol
go.drugbank.com/drugs/DB06943Experimental(3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiol is a solid. This compound belongs to the benzenesulfonamides. … These are organic compounds containing a sulfonamide group that is S-linked to a benzene ring. This substance is known to target disintegrin and metalloproteinase domain-containing protein 17.
Synonyms: (3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiolFenofibric acid
go.drugbank.com/drugs/DB13873ApprovedInvestigationalIt works to decrease elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, apolipoprotein B, while increasing high-density lipoprotein cholesterol. … Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia, and mixed dyslipidemia.
Mixtures: STAFEN®135 / 5 MG CAPSULAS, FENOVAS®20 MGCategories: Non-statin Hypolipidemic Agents Indicated for Hyperlipidemia(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide
go.drugbank.com/drugs/DB08564ExperimentalSynonyms: (2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(dimethylamino)but-2-enamideDichlorobenzyl alcohol
go.drugbank.com/drugs/DB13269Approved[L1113] On the other hand, dichlorobenzyl alcohol is categorized by the FDA in the inactive ingredient for approved drug products.[L2773] … [A33047] Dichlorobenzyl alcohol is considered as an active ingredient found in several marketed OTC products by Health Canada which has categorized this agent as an anatomical therapeutic chemical.
Mixtures: ซีพาคอล(R) อาร์เอ็กซ์, ซีพาคอล(R) อาร์เอ็กซ์Products: NEO BOROCILLINACAM-101
go.drugbank.com/drugs/DB18414InvestigationalCAM-101 is an allogeneic human platelet lysate product depleted of fibrinogen.