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Displaying results 461 - 470 of 5498 in total
  1. Drug

    Pomalidomide

    go.drugbank.com/drugs/DB08910
    ApprovedInvestigational

    Pomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. FDA approved on February 8, 2013.

    Products: POMALYST CAPSULE 1MG, Pomalyst Capsules 1mg
  2. Drug

    Nintedanib

    go.drugbank.com/drugs/DB09079
    ApprovedInvestigational

    [L8453,L8459] It was first approved for use in the United States in 2014.

    Products: OFEV SOFT CAPSULES 100MG, NINTEDANIB EG
  3. Drug

    Nicardipine

    go.drugbank.com/drugs/DB00622
    ApprovedInvestigational

    It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. [PubChem] … It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects.

    Products: Cardene 20mg Capsules, Cardene Cap 30mg
  4. Drug

    Midodrine

    go.drugbank.com/drugs/DB00211
    ApprovedInvestigational

    It is used as a vasoconstrictor agent in the treatment of hypotension.

    Products: Miron 10mg Tablets, MIDODRINA EG
  5. Drug

    Asciminib

    go.drugbank.com/drugs/DB12597
    ApprovedInvestigational

    [A241065] Asciminib is unique in that it acts as an allosteric inhibitor, binding at the myristoyl pocket of the BCR-ABL1 protein and locking it into an inactive conformation. … More specifically, it is an inhibitor of the ABL1 kinase activity of the BCR-ABL1 fusion protein[L38995] which serves as a driver of CML proliferation in most patients with the disease.

    Products: Scemblix 20mg film-coated tablet, Scemblix 40mg film-coated tablet
  6. Drug

    Baloxavir marboxil

    go.drugbank.com/drugs/DB13997
    ApprovedInvestigational

    [L4779] It was also approved by the European Commission on January 7, 2021.[L45241] … More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza virus proliferation.

    Products: XOFLUZA FILM COATED TABLETS 20MG, XOFLUZA FILM-COATED TABLET 20MG
  7. Drug

    Propafenone

    go.drugbank.com/drugs/DB01182
    ApprovedInvestigational

    It also has weak beta-blocking activity. The drug is generally well tolerated.

    Products: PROPAFENON CT 150MG FILMTA, PROPAFENONE EG
  8. Drug

    Riociguat

    go.drugbank.com/drugs/DB08931
    ApprovedInvestigational

    Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for the treatment of patients with inop...

    Products: ADEMPAS FILM-COATED TABLET 2.0mg, Adempas 1mg film-coated tablet
  9. Drug

    Asenapine

    go.drugbank.com/drugs/DB06216
    ApprovedInvestigational

    It is also for severe post-traumatic stress disorder nightmares in soldiers as an off-label use. FDA approved on August 13, 2009.

    Products: SAPHRIS SUBLINGUAL TABLET 10MG, SYCREST 10MG DILALTI TABLET, 100 TABLET
  10. Drug

    Vardenafil

    go.drugbank.com/drugs/DB00862
    Approved

    Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction. During sexual stimulation, nitric oxide (NO) is released...

    Products: LEVITRA 20MG TABLET, LEVITRA 10MG TABLET