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Nilutamide
go.drugbank.com/drugs/DB00665ApprovedInvestigationalNilutamide is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer. … Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors (but not for progestogen, estrogen, or glucocorticoid receptors).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 InhibitorsPipamperone
go.drugbank.com/drugs/DB09286Investigationaldrugs at this time, had significant anti-tryptamine activity. … In an effort to improve [haloperidol]'s pharmacological effects, Janssen discovered that pipamperone, an agent whose pharmacological profile was distinct from haloperidol and all other known antipsychotic
Oxypurinol
go.drugbank.com/drugs/DB05262InvestigationalOxypurinol, an inhibitor of xanthine oxidase, is a metabolite of allopurinol.
α-Methylfentanyl
go.drugbank.com/drugs/DB01557ExperimentalIllicitα-Methylfentanyl is an analog of fentanyl with opioid analgesic properties.
D-Leucine
go.drugbank.com/drugs/DB01746ExperimentalAn essential branched-chain amino acid important for hemoglobin formation. [PubChem]
Aniracetam
go.drugbank.com/drugs/DB04599InvestigationalCompound with anti-depressive properties used as a mental performance enhancer.
Synonyms: 1-p-anisoylpyrrolidin-2-oneXPro1595
go.drugbank.com/drugs/DB16454InvestigationalXPro1595 is an investigational dominant-negative protein that neutralizes soluble TNF.
Synonyms: HOMOSAPIENS TUMOR NECROSIS FACTOR,SOLUBLE FORM (V1>M, R31>C, C69>V, Y87>H, C101>A, A145>R), MONOMER, PEGYLATED ON CYSTEINE 31 : S-((3RS)-(2-((3-(.OMEGA.Famzeretcel
go.drugbank.com/drugs/DB17906InvestigationaljCell is an human retinal progenitor cell therapy for retinitis pigmentosa.
Barnidipine
go.drugbank.com/drugs/DB09227Investigationalafter a 1-year and 2-year follow-up period in 91% of the patients who had an initial response to the drug [A7842]. … Compared to several other calcium antagonists which are racemates, the barnidipine compound consisting of a single enantiomer may offer a high degree of pharmacological selectivity [A31567].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsGS-100
go.drugbank.com/drugs/DB18337InvestigationalGS-100 is an adeno-associated virus serotype 9 virus particle containing viral DNA that includes an expression cassette containing the human NGLY1 gene coding sequence