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Recombinant SARS-CoV-2 Vaccine (Sf9 Cell)
go.drugbank.com/drugs/DB16443InvestigationalThese promising results have secured a Phase I trial (NCT04530656) to evaluate the safety, efficacy, and immunogenicity in healthy Chinese participants. … The Recombinant SARS-CoV-2 Vaccine was created by inserting genes of the SARS-CoV-2 spike protein’s receptor-binding domain into a baculovirus expression system[F4738, A226853].
GEM-231
go.drugbank.com/drugs/DB05798InvestigationalMonoclonal antibodies are made in the laboratory and can locate and bind to cancer cells. … GEM231 is a second-generation antisense oligonucleotide targeting the mRNA of the R1alpha regulatory subunit of cAMP dependent protein kinase.
Alisertib
go.drugbank.com/drugs/DB05220InvestigationalAlisertib is a novel aurora A kinase inhibitor under investigation for the treatment of various forms of cancer.
PYM50018
go.drugbank.com/drugs/DB05126ExperimentalWhen administered orally to a transgenic pre-clinical model of ALS, PYM50018 delays the loss of muscle strength and extends survival time. … It is developed for the treatment of amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease).
NRP369
go.drugbank.com/drugs/DB06384ExperimentalNRP369 is an oxycodone derivative under investigation for the treatment of pain (moderate to moderately severe). NRP369 was developed by New River Pharmaceuticals as a backup therapeutic to [NRP290].
Prostaglandin G2
go.drugbank.com/drugs/DB03866ExperimentalA cyclic endoperoxide intermediate produced by the action of CYCLOOXYGENASE on ARACHIDONIC ACID. It is further converted by a series of specific enzymes to the series 2 prostaglandins. [PubChem]
Insulin beef
go.drugbank.com/drugs/DB09456ApprovedInsulin beef has been discontinued in the US and Canada since 2017.[L10827]
Oxatomide
go.drugbank.com/drugs/DB12877ApprovedOxatomide has been used in trials studying the treatment of Muscular Dystrophy, Duchenne.
ME-344
go.drugbank.com/drugs/DB13062InvestigationalME-344 has been used in trials studying the treatment of Solid Tumors.
Parthenolide
go.drugbank.com/drugs/DB13063ApprovedInvestigationalParthenolide has been used in trials studying the diagnostic of Allergic Contact Dermatitis.