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Displaying results 4721 - 4730 of 5261 in total
  1. Drug

    Dimethyl sulfoxide

    go.drugbank.com/drugs/DB01093
    ApprovedInvestigationalVet approved

    A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue dur...

  2. Drug

    Amifostine

    go.drugbank.com/drugs/DB01143
    ApprovedInvestigational

    A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.

  3. Drug

    Afimoxifene

    go.drugbank.com/drugs/DB04468
    Investigational

    It is being developed by Ascent Therapeutics.

  4. Drug

    AdPEDF

    go.drugbank.com/drugs/DB05138
    Experimental

    AdPEDF is under development for the treatment of wet age-related macular degeneration (AMD). It has been shown to rapidly elevate the intraocular AdPEDF protein levels in the eye, inhibit abnormal blood vessel growth, and cause abnormal ...

  5. Drug

    Tariquidar

    go.drugbank.com/drugs/DB06240
    Investigational

  6. Drug

    Ty800

    go.drugbank.com/drugs/DB04989
    Investigational

    It is being developed by AVANT Immunotherapeutics, Inc.

  7. Drug

    GS030-DP

    go.drugbank.com/drugs/DB17847
    Investigational

    It targets retinal ganglion cells that encodes a light-sensitive channelrhodopsin, ChrimsonR-tdTomato (ChR-tdT), delivered by an AAV2.7m8 vector.

  8. Drug

    AC-003

    go.drugbank.com/drugs/DB22691
    Investigational

    [L53458,L53463] By inhibiting RIPK1 kinase activity, AC-003 thereby inhibits RIPK1-mediated cell death and inflammation.

  9. Drug

    PG-530742

    go.drugbank.com/drugs/DB05495
    Investigational

    By inhibiting these MMPs, it potentially limits cartilage degradation and disease progression.

  10. Drug

    Meglutol

    go.drugbank.com/drugs/DB04377
    Experimental

    It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which