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Displaying results 4731 - 4740 of 10000 in total
  1. Drug

    Plasma protein fraction (human)

    go.drugbank.com/drugs/DB13968
    ApprovedInvestigational

    It is also stated that no more than 1% of the total protein should be gamma globulin.[L2260] PPFh is a sterile, frozen solution of solvent/detergent treated human plasma. … The composition of PPFh should be 5% of protein from which 83% should consist of albumin and no more of 17% should be globulin.

    Mixtures: Varitect CP 25 I.E./ml InfusionslösungProducts: PLASMANATE - 5% (50 ML VIAL), PLASMANATE - 5% ( 250 ML VIAL )
  2. Drug

    Clopidogrel

    go.drugbank.com/drugs/DB00758
    ApprovedInvestigational

    Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke. … in recent MI, stroke, or established peripheral arterial disease,[L7213] It has been shown to be superior to [aspirin] in reducing cardiovascular outcomes in patients with cardiovascular disease and

    Mixtures: ATELIT-DUO® 75/100 MG TABLETAS, KLOGEL-A 75/75 MG KAPSUL, 30 ADETCategories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substrates
  3. Drug

    Iobitridol

    go.drugbank.com/drugs/DB12407
    ApprovedWithdrawn

    Iobitridol has been used in trials studying the diagnostic of Diagnostic Imaging, Coronary Artery Disease, Type 2 Diabetes Mellitus, and Coronary Atherosclerosis.

    Categories: Compounds used in a research, industrial, or household setting, X-Ray Contrast Media, IodinatedProducts: XENETİX 300 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 100 ML, Xenetix 250 (250 mg Jod/ml) - Parenterale Röntgenkontrastmittellösung
  4. Drug

    Anifrolumab

    go.drugbank.com/drugs/DB11976
    ApprovedInvestigational

    Anifrolumab, or MEDI-546, is a type 1 interferon receptor (IFNAR) inhibiting IgG1κ monoclonal antibody indicated in the treatment of adults with moderate to severe systemic lupus erythematosus. … [A237079,L34929] Three monoclonal antibodies (anifrolumab, [rontalizumab], and [sifalimumab]) that target the type 1 interferon pathway entered clinical trials as potential treatments for systemic lupus

    Categories: Type I Interferon Receptor AntagonistProducts: Saphnelo 300 mg/2 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 ADET
  5. Drug

    Arbutin

    go.drugbank.com/drugs/DB11217
    Approved

    Extracted from the dried leaves of bearberry plant in the genus _Arctostaphylos_ and other plants commonly in the _Ericaceae_ family, arbutin is a beta-D-glucopyranoside of [DB09526]. … It has also been used as an anti-infective for the urinary system as well as a diuretic [F43].

    Synonyms: p-hydroxyphenyl β-D-glucoside, hydroquinone O-β-D-glucopyranosideMixtures: Dr G Whitening REFORMER by EGF, Dr G Whitening FORTIFIER by EGF
  6. Drug

    Hexamidine

    go.drugbank.com/drugs/DB03808
    ApprovedInvestigational

    Mixtures: Imazol duo 10 mg/g + 2,5 mg/g CremeProducts: DESOMEDINE EYE DROPS 1 mg/ml
  7. Drug

    Tefidsogene civaparvovec

    go.drugbank.com/drugs/DB16789
    Investigational

    It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes … Tefidsogene civaparvovec, formerly known as SB-913, is an investigational therapy for genome editing.

    Synonyms: A RECOMBINANT NON-REPLICATING ADENO-ASSOCIATED VIRUS TYPE 2/6 (RAAV REP2-CAP6) VECTOR, WHICH CONTAINS A PROMOTER-LESS HUMAN IDURONATE 2-SULFATASE (HIDS) TRANSGENE CASSETTE, ENCODING PARTS OF EXON 1 PLUS, EXONS 2-9 FROM HIDS AND A SPLICE ACCEPTOR SITE (SA)
  8. Drug

    Mebeverine

    go.drugbank.com/drugs/DB12554
    ApprovedInvestigationalWithdrawn

    Mebeverine has been investigated for the treatment of Irritable Bowel Syndrome and Post-cholecystectomy Gastrointestinal Spasms.

    Mixtures: ARLUY DUO, ARLUY-DUOProducts: DUSPATALIN® CÁPSULA DE LIBERACIÓN PROLONGADA 200 MG, DUSPATALIN® 135 MG
  9. Drug

    Acemetacin

    go.drugbank.com/drugs/DB13783
    ApprovedInvestigational

    [A31352] In clinical trials, acemetacin exhibits a better gastric tolerability compared to its active metabolite indometacin.[T50] It was developed by E. … Acemetacin is a carboxymethyl ester of indometacin.

    Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 2-RingProducts: RANTUDIL ® LP 90 MG CAPSULAS DE LIBERACIÓN PROLONGADA, RANTUDIL® 60 MG CAPSULAS
  10. Drug

    Nelistotug

    go.drugbank.com/drugs/DB19334
    Investigational

    Nelistotug is under investigation in clinical trial NCT06062420 (A Platform Study of Novel Immunotherapy Combinations as First-line Treatment in Participants With PD-L1 Positive Recurrent/metastatic Squamous … Cell Carcinoma of the Head and Neck- GALAXIES H&N-202).

    Synonyms: Gamma1 heavy chain Homo sapiens (1-452) [VH(Homo sapiens IGHV1-69*01 (95.9%) -(IGHD)-IGHJ1*01 (90.9%) L123>T (117), CDR-IMGT [8.8.15](26-33.51-58.97-111)) (1-122) -Homo sapiens IGHG1*01 (100%), G1m17,1, Nelistotug (immunoglobulin G1-kappa, anti-[Homo sapiens CD96 (T cell activation increased late expression, TACTILE, T-cell surface protein tactile)], Homo sapiens monoclonal antibody)