Plasma protein fraction (human)

DB13968ApprovedInvestigationalProtein Based TherapiesHemostaticsHuman Serum Albumin

Plasma protein fraction (human) is a plasma protein solution used to treat coagulation factor deficiencies, reverse anticoagulant effects, and shock from a loss of plasma fluids, and is also used in plasma exchange procedures. The plasma protein fraction human (PPFh) is defined as a sterile solution of proteins composed mainly of albumin and globulin derived from human plasma.

Mechanism
Curator reviewed · 1 reference
Primary indication
PPFh is used as a replacement therapy in patients with complex deficiencies of coagulation factors such as coagulopathy.Curator reviewed · 15 structured indications
First approval
Canada, 2011 · United States, 2013
Also known as
Human plasma protein · Human plasma protein fraction · Human plasma proteins · Plasma protein fraction · Plasma protein fraction human

Resolves to

Clinical / RWD

What you can answer from here — as of July 07, 2026

5Protein targetsEach mapped to UniProt, with action and pharmacological action
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14Clinical trialsPhase, status and sponsor resolved per trial
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15Structured indicationsCondition, population, route and combination as fields, not prose
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28Marketed productsAcross 8 countries and 13 labellers
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12+ReferencesStructured and connected to the statements they support
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