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Bevirimat
go.drugbank.com/drugs/DB06581InvestigationalIt is not currently FDA-approved, but is undergoing clinical trials conducted by the pharmaceutical company Panacos.
Phenserine
go.drugbank.com/drugs/DB04892InvestigationalUnlike currently marketed AChE inhibitors, it has a dual mechanism of action that also includes anti-amyloid activity, which may confer disease-modifying effects in patients with AD.
OT-551
go.drugbank.com/drugs/DB05650InvestigationalIt is intended to treat Age-related macular Degeneration (AMD), and preclinical research results indicate additional uses for OT-551, including treatment of early stage and advanced dry age-related macular
Deoxyribonuclease I
go.drugbank.com/drugs/DB16523InvestigationalIt is normally found in saliva, urine, pancreatic secretions, and blood[A227723].
MVA-BN-brachyury-TRICOM vaccine
go.drugbank.com/drugs/DB17424InvestigationalIt is composed of recombinant vaccinia viral vector, modified vaccinia Ankara-Bavarian Nordic (MVA-BN), encoding the human transcription factor and tumour-associated antigen (TAA) brachyury, and a triad
Talniflumate
go.drugbank.com/drugs/DB09295InvestigationalIn addition, it is used in inflammatory conditions such as rheumatoid arthritis.
Aleglitazar
go.drugbank.com/drugs/DB08915InvestigationalIt is being investigated for use in patients with type II diabetes to reduce their risks of cardiovascular mortality and morbidity.
Tunicamycin
go.drugbank.com/drugs/DB13172ExperimentalIt is used as an experimental tool to induce unfolded protein response. Tunicamycin is produced by Streptomyces clavuligerus and Streptomyces lysosuperficus bacteria along with several other species.
Recombinant SARS-CoV-2 Vaccine (Sf9 Cell)
go.drugbank.com/drugs/DB16443InvestigationalIt also provided protection in non-human primates to an in vivo challenge with SARS-CoV-2[A226853].
IMM-101
go.drugbank.com/drugs/DB15850InvestigationalIt has shown to be safe and well tolerated to complement conventional cancer therapy for patients with melanoma and pancreatic ductal adenocarcinoma[A220013,A220018,A220023].