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Displaying results 4741 - 4750 of 8700 in total
  1. Drug

    Diroximel fumarate

    go.drugbank.com/drugs/DB14783
    ApprovedInvestigational

    [A176474] It is the main cause of neurological disability not caused by trauma in the young adult population of both North America and Europe. … Multiple Sclerosis (MS) is a chronic, debilitating neurological disease that can lead to profound cognitive and physical symptoms, severely affecting quality of life.

  2. Drug

    Tesevatinib

    go.drugbank.com/drugs/DB11973
    Investigational

    In addition, tesevatinib inhibits EphB4, an RTK that is highly expressed in many human tumors and plays a role in promoting angiogenesis.

    Categories: Receptor, EphB4, antagonists & inhibitors, Receptor, ErbB-2, antagonists & inhibitors
  3. Drug

    Mitiglinide

    go.drugbank.com/drugs/DB01252
    Investigational

    Mitiglinide is a drug for the treatment of type 2 diabetes. It may stimulate insulin secretion in beta-cells by closing off ATP dependant potassium ion channels.

  4. Drug

    Sodium bisulfite

    go.drugbank.com/drugs/DB14015
    ApprovedWithdrawn

    Sodium bisulfite has been used externally for parasitic skin diseases and as a gastrointestinal antiseptic.

    Mixtures: NEOFLEKS IZOPLEN-P % 5 DEKSTROZLU DENGELI ELEKTROLIT IÇEREN INFÜZYON IÇIN ÇÖZELTI 1000 ML SETLI, NEOFLEKS IZOPLEN-P % 5 DEKSTROZLU DENGELI ELEKTROLIT IÇEREN INFÜZYON IÇIN ÇÖZELTI 250 ML SETLI
  5. Drug

    Isoxaflutole

    go.drugbank.com/drugs/DB12938
    ApprovedWithdrawn

    Balance has been investigated for the treatment of Chronic Renal Failure and Peritoneal Membrane Disorder.

  6. Drug

    99mTc-glucarate

    go.drugbank.com/drugs/DB05810
    Investigational

    99mTc-glucarate(GLA) is an agent for non-invasive detection of breast tumours.

  7. Drug

    AEOL-10150

    go.drugbank.com/drugs/DB05874
    Experimental

    AEOL 10150 is developed by Aeolus as a therapeutic agents based on its proprietary small molecule catalytic antioxidants.

  8. Drug

    Estramustine

    go.drugbank.com/drugs/DB01196
    ApprovedWithdrawn

    A nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.

    Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitors
  9. Drug

    Dinoprost tromethamine

    go.drugbank.com/drugs/DB01160
    ApprovedVet approvedWithdrawn

    Dinoprost tromethamine may also be known as dinoprost trometamol, PGF2 alpha THAM, or prostaglandin F2 alpha tromethamine.

  10. Target

    P2 Purinoceptors

    go.drugbank.com/bio_entities/BE0009827
    Target

    Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system … Unlike other P2RX receptors, the P2X5 receptor is also permeable to chloride (PubMed:12761352). May play a supporting role in the inflammatory response (By similarity)

    Polypeptides: Lysophosphatidic acid receptor 4, Lysophosphatidic acid receptor 6Synonyms: LPA receptor 4, LPA receptor 6