Search

Displaying results 4751 - 4760 of 10000 in total
  1. Drug

    OPC-14523

    go.drugbank.com/drugs/DB05422
    Experimental

    OPC-14523 is an antidepressant drug developed by Otsuka America Pharmaceutical.

  2. Drug

    Canis lupus familiaris hair

    go.drugbank.com/drugs/DB10867
    Approved

    Domestic dog hair is used in allergenic testing.

    Mixtures: Animal Allergens, UF Dog Hair-Dander Canis spp, Dog Hair and Epithelia
  3. Drug

    EP-2104R

    go.drugbank.com/drugs/DB05675
    Experimental

    EP-2104R is an imaging pharmaceutical under development for the detection of blood clots. It is the first targeted high-resolution technique designed to visualize blood clots directly. … It is being developed by EPIX Pharmaceuticals, Inc.

    Categories: Amino Acids, Peptides, and Proteins
  4. Drug

    Procaterol

    go.drugbank.com/drugs/DB01366
    ApprovedWithdrawn

    It is a potent bronchodilator that may be administered orally or by aerosol inhalation.

  5. Drug

    rhMBL

    go.drugbank.com/drugs/DB05237
    Investigational

    rhMBL is a protein therapeutic being developed by Enzon for the prevention and treatment of severe infections in individuals with low levels of Mannose-Binding Lectin (MBL). … MBL forms different oligomers but must form at least a tetramer to be active.

  6. Drug

    Zilovertamab vedotin

    go.drugbank.com/drugs/DB18457
    Investigational

    Zilovertamab vedotin is an Antibody-drug conjugate (ADC) comprising an anti-ROR1 monoclonal antibody (UC-961), a proteolytically cleavable maleimidocaproyl-valine-citrulline-para-aminobenzoate linker ( … mc-vc-PAB), and a monomethyl auristatin E (MMAE) cytotoxin.

  7. Drug

    Pirbuterol

    go.drugbank.com/drugs/DB01291
    ApprovedWithdrawn

    In vitro studies and in vivo pharmacologic studies have demonstrated that pirbuterol has a preferential effect on beta-2 Adrenergic receptors compared with isoproterenol. … Increased c-AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells.

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Tertomotide

    go.drugbank.com/drugs/DB12747
    Investigational

    It is a peptide vaccine that activates the immune system so that it recognizes and kills cancer cells. It is being developed by Pharmexa A/S. … Tertomotide is under investigation in clinical trial NCT01223209 (A Study, Combination, Immunologic Study of LTX-315 as adjunct to tertomotide in Patients Following Curative Surgery for Carcinoma).

  9. Drug

    Buformin

    go.drugbank.com/drugs/DB04830
    ApprovedWithdrawn

    Buformin is an anti-diabetic drug of the biguanide class, chemically related to metformin and phenformin. … It was withdrawn from the market in most countries due to a high risk of causing lactic acidosis.

    Categories: Drugs Used in Diabetes, Alimentary Tract and Metabolism
  10. Drug

    Trilaciclib

    go.drugbank.com/drugs/DB15442
    ApprovedInvestigational

    [L31828] CDK4 and CDK6 inhibitors have been investigated since the mid 1990s for their use in tumorigenesis and chemotherapy.[A229323] Trilaciclib was first described in the literature in 2016. … Trilaciclib, or G1T28, is a CDK4 and CDK6 inhibitor, indicated to reduce the incidence of chemotherapy induced myelosuppression in patients before topotecan-containing or platinum and etoposide-containing

    Categories: MATE 2-K Inhibitors