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Poractant alfa
go.drugbank.com/drugs/DB09113ApprovedInvestigationalPoractant alfa is a creamy white suspension of this extract in 0.9% sodium chloride solution. It contains no preservatives. … Poractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada.
Products: CUROSURF ® 3.0 ML, CUROSURF 240 MG/3 ML INTRATRAKEAL SUSPANSIYON IÇEREN FLAKON, 1 ADETElamipretide
go.drugbank.com/drugs/DB11981ApprovedInvestigational[A274436] Elamipretide is a synthetic tetrapeptide that selectively binds to cardiolipin, a phospholipid in the inner mitochondrial membrane. … [L54036] In September 2025, the U.S.
Categories: MATE 1 InhibitorsForeskin fibroblast (neonatal)
go.drugbank.com/drugs/DB10770ApprovedThe impact of diabetic foot ulcers (DFU) on individuals and society is devastating. Failure to observe proper wound care in this condition often results in amputation. … Dermagraft has only been available in the United States as an investigational device (IDE). Dermagraft for the treatment of diabetic foot ulcers was approved for sale in Canada in 1997.
Pomaglumetad methionil
go.drugbank.com/drugs/DB05096InvestigationalFor LY2140023, the active substance, LY404039, is thought to work by reducing the presynaptic release of another neurotransmitter, glutamate, in brain regions where mGlu2/3 receptors are expressed. … LY2140023 is an oral "prodrug," meaning it is devoid of intrinsic biological activity and, once administered, is metabolized to provide the active mGlu2/3 receptor agonist called LY404039.
Eflapegrastim
go.drugbank.com/drugs/DB15001ApprovedInvestigationalin which the patient develops an infection during a period of significant neutropenia. … the use of pharmacologic prophylaxis against FN in patients receiving high-risk regimens and those receiving intermediate-risk regimens who have ≥1 additional risk factor.
Ulobetasol
go.drugbank.com/drugs/DB00596Approved[A215597] Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses. … Ulobetasol is a highly potent corticosteroid.[A215597] It is structurally related to [clobetasol].
Mixtures: Ultravate X, Ultravate XSilmitasertib
go.drugbank.com/drugs/DB15408InvestigationalSilmitasertib is under investigation in clinical trial NCT03904862 (Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery).
Categories: Casein Kinase II, antagonists & inhibitors, Heterocyclic Compounds, 2-RingAzacitidine
go.drugbank.com/drugs/DB00928ApprovedInvestigational[A1415] The use of oral azacitidine for the treatment of AML in patients in complete remission was approved by the FDA in September 2020.[L35335] … Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-amino-1-beta-D-ribofuranosyl-s-triazin-2(1H)-one, 5 AzacitidineChloric acid
go.drugbank.com/drugs/DB14150ApprovedCategories: Compounds used in a research, industrial, or household settingHuman botulinum neurotoxin A/B immune globulin
go.drugbank.com/drugs/DB14115ApprovedInfant botulism is a rare infectious disease occurring in infants in which _Clostridium botulinum_ colonize the large intestine and being to produce botulinum neurotoxin directly in the gut. … [L39819,L39824] BabyBIG (human-derived botulism immunoglobulin) was approved for use by the FDA in 2003[L39814] and has since been used to treat more than 2100 cases of infant botulism.
Categories: Human Immunoglobulin GSynonyms: Botulism immune globulin IV human, Human botulinum neurotoxin A/B immune globulin