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Celastrol
go.drugbank.com/drugs/DB18736ExperimentalCelastrol is a pentacyclic triterpenoid isolated from the root extracts of _Tripterygium wilfordii_.[L50567]
Synonyms: 24-nor-d:a-friedooleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-2-oxo-Candesartan
go.drugbank.com/drugs/DB13919InvestigationalCandesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is available as a prodrug in the form of [candesartan cilexetil].
Darusentan
go.drugbank.com/drugs/DB04883InvestigationalIt is being evaluated as a treatment for congestive heart failure and hypertension.
ORG-34517
go.drugbank.com/drugs/DB05423InvestigationalORG-34517 is currently under investigation by Organon for the treatment of depression.
Fluorodopa (18F)
go.drugbank.com/drugs/DB13848ApprovedInvestigationalFluorodopa F 18 is a fluorinated analog of [levodopa] used as a diagnostic agent for positron emission tomography (PET) in the evaluation of Parkinsonian syndromes.
Sitimagene ceradenovec
go.drugbank.com/drugs/DB04907ExperimentalIt is being developed by Ark Therapeutics. … Sitimagene ceradenovec is a novel gene-based product for the treatment of patients with operable high grade glioma, a type of malignant brain tumour, given in addition to standard surgery and radiotherapy
Carbomycin
go.drugbank.com/drugs/DB11383ExperimentalVet approvedThis antibacterial is obtained from _Streptomyces halstedii_ and it presents a large inhibitory effect against Gram-positive bacteria and some Mycoplasma strains. … The structure of carbomycin was generated in 1957 by Robert Woodward and later modified in 1965.
Lamivudine
go.drugbank.com/drugs/DB00709ApprovedInvestigationalA reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseProducts: LAMIVUDINA MK COMPRIMIDOS RECUBIERTOSAmubarvimab
go.drugbank.com/drugs/DB16493InvestigationalAmubarvimab (BRII-196) was under investigation in clinical trials (NCT04691180 and NCT04787211) to treat COVID-19, focusing on its safety, tolerability, and efficacy.
Categories: Experimental Unapproved Treatments for COVID-19MDX-214
go.drugbank.com/drugs/DB06110ExperimentalIt is developed for the treatment of EGF-R overexpressing cancers. … MDX-214 consists of recombinant human epidermal growth factor (EGF) genetically linked to a fully human antibody fragment that is designed to activate cytotoxic killing of cancer cells by immune effector