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OM85
go.drugbank.com/drugs/DB16533InvestigationalOM-85, a bacterial extract, is an immunomodulator of interferon-β production and inflammasome activity.
AAV-RPE65
go.drugbank.com/drugs/DB18343ExperimentalAAV-RPE65 is an adenovirus associated viral vector serotype 5 containing the human RPE65 gene
Cannabinor
go.drugbank.com/drugs/DB05048ExperimentalCannabinor, a synthetic CB2-selective agonist, is in Phase 2 clinical testing as an analgesic.
Epirizole
go.drugbank.com/drugs/DB08991ExperimentalEpirizole is an oral nonsteroidal anti-inflammatory drug (NSAID) used for muscle and joint pain.
Danofloxacin
go.drugbank.com/drugs/DB11393ExperimentalVet approvedDanofloxacin is an antibiotic agent from the family of the fluoroquinolones used in veterinary medicine.
Mecasermin rinfabate
go.drugbank.com/drugs/DB14751ApprovedInvestigationalMecasermin rinfabate is approved for severe primary insulin-like growth factor (IGF) deficiency or in patients with GH gene deletion who have developed antibodies to growth hormone (GH) . Mecasermin rinfabate is similar to DB01277 in tha...
Pralsetinib
go.drugbank.com/drugs/DB15822ApprovedInvestigationalPralsetinib, similar to the previously approved selpercatinib, is a kinase inhibitor with enhanced specificity for RET tyrosine kinase receptors (RTKs) over other RTK classes. Enhanced RET (Rearranged during transfection) oncogene expres...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesChlormadinone acetate
go.drugbank.com/drugs/DB15903ApprovedWithdrawn[L43942,L42975] Chlormadinone acetate continues to be used in other countries due to its high contraceptive efficacy and tolerability.[A254422,L33974]
Resmetirom
go.drugbank.com/drugs/DB12914ApprovedInvestigationalOn March 14, 2024, it was approved by the FDA as the first treatment of liver fibrosis due to noncirrhotic non-alcoholic steatohepatitis (NASH), which is a form of non-alcoholic fatty liver disease (NAFLD
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsLasalocid
go.drugbank.com/drugs/DB11423ExperimentalVet approvedLasalocid is an agent that presents antibacterial and coccidiostat activities. It is produced by strains of _Streptomyces lasaliensis_.