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Capsaicin
go.drugbank.com/drugs/DB06774ApprovedInvestigationalCapsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements … Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations.
Mixtures: NuDroxiPAK E-400, Trubrexa Patch ERSynonyms: (E)-8-Methyl-N-vanillyl-6-nonenamide, trans-8-Methyl-N-vanillyl-6-nonenamidePetrolatum
go.drugbank.com/drugs/DB11058ApprovedInvestigationalIt is used as an ointment base, topical protectant, and lubricant.
Mixtures: Veradex-E, Ea Eight Hr Lip Sheer TintsCategories: Compounds used in a research, industrial, or household settingIndomethacin
go.drugbank.com/drugs/DB00328ApprovedInvestigationalAlthough deemed effective in reducing ocular inflammation in clinical studies, topical NSAIDs were also associated with a potential reduction in corneal sensitivity accompanied by an increased risk of … Indometacin was first discovered in 1963 and it was first approved for use in the U.S. by the Food and Drug Administration in 1965, [A486] along with other acetic acid derivatives such as [diclofenac]
Products: Indomethacin ERLansoprazole
go.drugbank.com/drugs/DB00448ApprovedInvestigational[A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD)
Products: LANSOPRAZOLO EG, LANSOPRAZOLO EG STADAAmiodarone
go.drugbank.com/drugs/DB01118ApprovedInvestigational[A36817] Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. … Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings.
Synonyms: 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuranProducts: AMIODARONE EGItraconazole
go.drugbank.com/drugs/DB01167ApprovedInvestigational[L50051] Itraconazole was first approved in the US in 1992 [L50056] and is available orally. … While the intravenous formulation of the drug was formerly available, it was discontinued in the US in 2007.[A263232]
Products: ITRACONAZOLO EGPhenytoin
go.drugbank.com/drugs/DB00252ApprovedInvestigationalVet approved[A189219,A35884] Both parenteral and oral formulations of phenytoin are available on the market.[A189219] … [A33595,A188832,A189219] Since it's introduction about 80 years ago, phenytoin has not only been established as an effective anti-epileptic, but has also been investigated for several other indications
Products: Phenytoin ERIsotretinoin
go.drugbank.com/drugs/DB00982ApprovedInvestigational[L6574] Isotretinoin is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the United States. … [L6579] The first isotretinoin-containing product was FDA approved on 7 May 1982.[L6574]
Categories: Retinoids for Topical Use in AcneProducts: ISOTRETINOINA EGGlycodelin
go.drugbank.com/bio_entities/BE0003957TargetHumansGlycodelin-F inhibits spermatozoa-zona pellucida binding and significantly suppresses progesterone-induced acrosome reaction of spermatozoa (PubMed:12672671).
Synonyms: Progesterone-associated endometrial proteinDasatinib
go.drugbank.com/drugs/DB01254ApprovedInvestigational[A2226] The use of dasatinib was first approved by the FDA in 2006.[L45171,L45186] … [A2226,A11377] Also, mutations in the kinase domain of BCR-ABL may lead to relapse during imatinib treatment.
Synonyms: N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamideProducts: DASATINIB EG