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Pravastatin
go.drugbank.com/drugs/DB00175ApprovedInvestigational[L6142] Pravastatin is made through a fermentation process in which [mevastatin] is first obtained. … It was the first statin administered as the active form and not as a prodrug.[T274] This drug was developed by Sankyo Co.
Synonyms: (+)-(3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(S)-2-methylbutyryl]oxy}-1,2,6,7,8,8a-hexahydro-1-naphthyl]heptanoic acidMixtures: PRAVAFEN® CAPSULASClopidogrel
go.drugbank.com/drugs/DB00758ApprovedInvestigationalClopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke. … ,L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent
Mixtures: ATELIT-DUO® 75/100 MG TABLETAS, KLOGEL-A 75/75 MG KAPSUL, 30 ADETCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesAtractylodes lancea root
go.drugbank.com/drugs/DB14693ApprovedInvestigationalSynonyms: Mao cang zhu rhizomeMedroxyprogesterone acetate
go.drugbank.com/drugs/DB00603ApprovedInvestigational[A14848] MPA can be use to treat secondary amenorrhea, endometrial hyperplasia, abnormal uterine bleeding, osteoporosis, vasomotor symptoms in menopause, vulvar and vaginal atrophy, prevent pregnancy, … Medroxyprogesterone acetate (MPA) is a [progesterone] derivative that is more resistant to metabolism for improved pharmacokinetic properties.
Mixtures: DIVICONT TABLETAS 1 MG/5 MG, FEMELIN®Categories: Pregnen (4) Derivatives, P-glycoprotein inhibitorsZinc gluconate
go.drugbank.com/drugs/DB11248ApprovedInvestigationalVet approvedStudies show that zinc may be better absorbed in humans in the gluconate form [A32412], [L2105], however, results from other studies may vary. … Studies suggest that administration of zinc along with new low osmolarity oral rehydration solutions/salts (oral rehydration solution), may reduce both the duration and severity of diarrheal episodes for
Mixtures: Citrate De Calcium Plus Vitamine D Et Zinc, PEDIALYTE ® MAX 60 MEQ CON ZINCProducts: ZINC INJECTABLE A 1mg/ml, solution injectable pour perfusion, Zink Aguettant 1 mg/ml Konzentrat zur Herstellung einer InfusionslösungPemetrexed
go.drugbank.com/drugs/DB00642ApprovedInvestigationalPemetrexed was first approved by the FDA in February 4, 2004.[A253907] … Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: PEMETREXED 500 MG POLVO LIOFILIZADO PARA SOLUCIÓN DE INFUSIÓN., PEMETREXED DR. REDDY'SColistimethate
go.drugbank.com/drugs/DB01111ApprovedInvestigationalVet approvedColistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms.
Products: COLISTIMETATO DE SODIO 2 MUI, COLISTIMETATO DE SODIODimenhydrinate
go.drugbank.com/drugs/DB00985ApprovedInvestigational[L32995] Early research into dimenhydrinate focused on its role as an antihistamine for urticaria; the treatment of motion sickness was an accidental discovery. … [A1539] Dimenhydrinate was granted FDA approval on 31 May 1972.[L32975]
Synonyms: 8-chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1), N,N-dimethyl-2-diphenylmethoxyethylamine 8-chlorotheophyllinateInternational brands: Vomex AMetoclopramide
go.drugbank.com/drugs/DB01233ApprovedInvestigational[A184934] Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to gastroesophageal reflux disease (GERD). … It can also be used to prevent nausea or vomiting associated with chemotherapy or certain surgical or diagnostic procedures.
Mixtures: CLIFAR® GOTAS, PLASIL®ENZIMATICOCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesCetylpyridinium
go.drugbank.com/drugs/DB11073ApprovedInvestigationalIn these products, it generally mediates an antiseptic activity and protective action against dental plaque and reducing gingivitis. … Its salt form, cetylpyridinium chloride, is typically found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays.
Synonyms: 1-hexadecylpyridiniumMixtures: Kank-A, NORAVER P TABLETAS DE DISOLUCIÓN BUCAL