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Folic acid
go.drugbank.com/drugs/DB00158ApprovedInvestigationalNutraceuticalVet approvedAs a result, supplementation with 1-5mg of folic acid is recommended to prevent deficiency and a number of side effects associated with MTX therapy including mouth ulcers and gastrointestinal irritation … Folic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis.
Mixtures: FERLOS 100 MG/0.35 MG TABLET, 30 ADET, MALTOFER FOL 100 MG/0.35 MG TABLET, 30 ADETCategories: Heterocyclic Compounds, 2-RingOlaparib
go.drugbank.com/drugs/DB09074ApprovedInvestigational[L41100, L40908, L43792] It was first approved by the FDA and EU in December 2014,[A246020] and by Health Canada in April 2016.[L42820] … [L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell
Synonyms: 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-oneCategories: MATE 2 Inhibitors, MATE 2-K InhibitorsCetirizine
go.drugbank.com/drugs/DB00341ApprovedInvestigationalThe prevalence of allergic rhinitis in the United States is about 15% according to physician diagnoses, and up to 30%, according to self-reported nasal symptoms. … Cetirizine, also commonly known as _Zyrtec_, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal
Mixtures: Cetirizine HCl and Pseudoephedrine HCl ER, Cetirizine HCl and Pseudoephedrine HCl ERProducts: CETIRIZINA EG, H-E-B Allergy ReliefMevonlerbart
go.drugbank.com/drugs/DB19416InvestigationalMevonlerbart is under investigation in clinical trial NCT06602726 (A Study to Demonstrate How Well REGN1908-1909 Works in Reducing Ocular Allergy Signs and Symptoms in Adult Participants With Cat Allergy
Synonyms: gamma4 heavy chain Homo sapiens (1-442) [VH (Homo sapiens IGHV3-23*04 (94.9%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.8] (26-33.51-58.97-104)) (1-115)-Homo sapiens IGHG4*01, G4v5 h P10, nG4m(a) CH2 L92, (CH1(116-213), hinge 1-12 S10>P (223) (214-225), CH2Fluvoxamine
go.drugbank.com/drugs/DB00176ApprovedInvestigationalIt was launched in the US in December 1994 and in Japan in June 1999. As of the end of 1995, more than 10 million patients worldwide have been treated with fluvoxamine. … Though it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: FLUVOXAMINA EG, REVOXIN 100 MG FILM TABLET, 30 ADETCilostazol
go.drugbank.com/drugs/DB01166ApprovedInvestigationalCilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been used in the symptomatic treatment of intermittent claudication in patients with peripheral ischaemia … It is marketed under the brand name Pletal by Otsuka Pharmaceutical Co.. Cilostazol works by inhibiting both primary and secondary aggregation and reducing calcium-induced contractions.
Synonyms: 3,4-dihydro-6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-2(1H)-quinolinone, 6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-2(1H)-quinolinoneCategories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household settingCenobamate
go.drugbank.com/drugs/DB06119ApprovedInvestigational[L10653] Cenobamate was granted FDA approval on 21 November 2019.[L10653] … [A188442,L10653] The exact mechanism of action has not been described in the literature, though it positively modulates GABA<sub>A</sub> and inhibits voltage gated sodium channels.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersProducts: XCOPRI TITRATION PACK 50 mg, 100 mg, XCOPRI MAINTENANCE PACK 100 mg, 150 mgCitalopram
go.drugbank.com/drugs/DB00215ApprovedInvestigationalIt is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs. … [A261316,A14720] Specifically, it has a very minimal effect on dopamine and norepinephrine transportation and virtually no affinity for muscarinic, histaminergic, or GABAergic receptors.
Mixtures: Sentralopram AM-10Categories: Serotonin 5-HT2 Receptor Antagonists, Cytochrome P-450 SubstratesRocuronium
go.drugbank.com/drugs/DB00728ApprovedInvestigationalIt is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery … Introduced in 1994, rocuronium has rapid onset, and intermediate duration of action. It is commonly marketed under the trade names Zemuron and Esmeron.
Products: Rocuroniumbromid Aguettant 10 mg/ml Injektionslösung in einer Fertigspritze, ANTARİN 100 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ, 10 ADETIsoniazid
go.drugbank.com/drugs/DB00951ApprovedInvestigationalIt remains the treatment of choice for tuberculosis.
Mixtures: ISOVIT 100 MG/25 MG TABLET, 500 TABLET, ISOVIT 100 MG/25 MG TABLET, 1000 TABLETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inhibitors