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Displaying results 4791 - 4800 of 10000 in total
  1. Drug

    Detomidine

    go.drugbank.com/drugs/DB11556
    InvestigationalVet approved

    This drug is prescribed by veterinarians and is marketed as _Dormosedan_. Currently, it is only approved by the FDA for use in horses but has been studied for use in other large animals. … Detomidine is an α2-adrenergic agonist that is used as a horse sedative. Normally, it is administered in the salt form, detomidine hydrochloride.

  2. Drug

    Rufinamide

    go.drugbank.com/drugs/DB06201
    Approved

    Clinical trials suggest its efficacy in the treatment of partial seizures. … Rufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy.

  3. Drug

    CCR5 mAb

    go.drugbank.com/drugs/DB05906
    Experimental

    It was generated by HGS using the Abgenix XenoMouse technology. … CCR5 mAb is a fully human monoclonal antibody that specifically recognizes and binds the chemokine receptor CCR5, which is known to be a key facilitator of infection with human immunodeficiency virus (

  4. Drug

    CX-717

    go.drugbank.com/drugs/DB05047
    IllicitInvestigational

    CX-717 is an ampakine compound previously investigated for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and Alzheimer's disease.

  5. Drug

    AVI-4020

    go.drugbank.com/drugs/DB05873
    Investigational

    AVI-4020 is a neugene antisense drug candidate for the treatment of patients with acute West Nile virus disease who have serious neurological impairment (WNV neuroinvasive disease).

  6. Drug

    Etirinotecan pegol

    go.drugbank.com/drugs/DB14951
    Investigational

    Etirinotecan pegol is under investigation in clinical trial NCT01663012 (Phase II NKTR-102 In Bevacizumab-Resistant High Grade Glioma).

    Categories: Topoisomerase II Inhibitors
  7. Drug

    Amifloxacin

    go.drugbank.com/drugs/DB20048
    Experimental

    Amifloxacin is a small molecule drug. The usage of the INN stem '-oxacin' in the name indicates that Amifloxacin is a nalidixic acid derivative antibacterial.

    Categories: Topoisomerase II Inhibitors
  8. Drug

    Trabedersen

    go.drugbank.com/drugs/DB05697
    Investigational

  9. Drug

    Cloxazolam

    go.drugbank.com/drugs/DB01553
    Experimental

    As well, it has also been studied in Japan in doses of 15-30mg/day as an adjunct in the treatment of intractable epilepsy, for which it has demonstrated effectiveness. … The usual dose of cloxazolam in adults is 3-12mg/day for anti-anxiety.

  10. Drug

    Recombinant Bacterial ACE2 Receptors-like Enzyme

    go.drugbank.com/drugs/DB15741
    Investigational

    B38-CAP is an ACE2-like enzyme which decreases angiotensin II levels. It is being investigated for treating hypertension, myocardial fibrosis, and cardiac dysfunction. … B38-CAP is structured as a carboxypeptidase and derived from _Paenibacillus sp._ The molecule, an Angiotensin Converting Enzyme 2 (ACE2)-like enzyme, shares structural similarities to the mammalian ACE2