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Furafylline
go.drugbank.com/drugs/DB14029ExperimentalFurafylline is a derivative of methylxanthine derivative. It was developed on the context of asthma as a long-acting alternative for [theophylline].
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Heterocyclic Compounds, 2-Ringbeta-Sitosterol
go.drugbank.com/drugs/DB14038InvestigationalActive fraction of Solanum trilobatum; reduces side-effects of radiation-induced toxicity.
Synonyms: (3β)-Stigmast-5-en-3-ol, (-)-β-SitosterolMixtures: BP Vit 3Palmidrol
go.drugbank.com/drugs/DB14043InvestigationalNutraceuticalA cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection. … Palmidrol is available for human use as a supplement (400 mg capsules) and as food for medical purposes In Italy and Spain (300 mg and 600 mg tablets).
Synonyms: N-(2-Hydroxyethyl)palmitamide, N-palmitoylethanolamineDichlorobenzene
go.drugbank.com/drugs/DB14046ApprovedWithdrawnIt is a constituent of the ear-wax removal product Cerumol. … Dichlorobenzene refers to any of, or a mixture of, three isomers consisting of benzene in which two of the hydrogen atoms are replaced by chlorine atoms: ortho-, meta-, and paradichlorobenzene.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 Substrates(S)-Warfarin
go.drugbank.com/drugs/DB14055InvestigationalS-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.[A7166] … Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways.
Synonyms: (S)-4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone, 4-hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-chromen-2-oneCategories: Vitamin K Antagonists, Cytochrome P-450 SubstratesDexverapamil
go.drugbank.com/drugs/DB14063ExperimentalSynonyms: (R)-verapamil, (+)-(R)-verapamilCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesEmopamil
go.drugbank.com/drugs/DB14064ExperimentalPrevents renal injury after warm & cold ischemia.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesLomerizine
go.drugbank.com/drugs/DB14065ExperimentalLomerizine is a diphenylmethylpiperazine calcium channel blocker[A245378, A245383] with relatively selective central nervous system (CNS) effects.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesONT-093
go.drugbank.com/drugs/DB14069ExperimentalONT-093 is an orally bioavailable inhibitor of P-glycoprotein (P-gp). … In pre-clinical studies, ONT-093 could inhibit P-gp and reverse multidrug resistance at nM concentrations with no effect on paclitaxel pharmacokinetics.
Categories: P-glycoprotein inhibitors, Heterocyclic Compounds, 1-Ring