DB14065ExperimentalSmall molecule
Lomerizine is a diphenylmethylpiperazine calcium channel blocker with relatively selective central nervous system (CNS) effects. This drug is used to prophylactically treat migraines and is also being investigated against eye-related...
- Mechanism
- Curator reviewed
Pharmacologically active on ATP-dependent translocase ABCB1
- Formula / weight
- C27H30F2N2O3 · 468.545 g/mol (avg)
- Also known as
- Lomerazine
Resolves to
Structure
InChIKey
JQSAYKKFZOSZGJ-UHFFFAOYSA-NSMILESCOC1=CC=C(CN2CCN(CC2)C(C2=CC=C(F)C=C2)C2=CC=C(F)C=C2)C(OC)=C1OCTransporters
What you can answer from here — as of August 30, 2026
3Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
1TransporterSubstrate / inhibitor direction, not just membershipListed above
Which drugs share a target with Lomerizine, and which of those have an active Phase 3 trial?
Create a free account or log in to explore the full data card.
Create Account