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Displaying results 4801 - 4810 of 10000 in total
  1. Drug

    Darapladib

    go.drugbank.com/drugs/DB06311
    Investigational

  2. Drug

    VT-111

    go.drugbank.com/drugs/DB05646
    Investigational

    VT-111 is a 55 kDa secreted glycoprotein belonging to a superfamily of proteins called SERPINS, which share a general structure and mechanism for proteinase inhibition.

  3. Drug

    Zunsemetinib

    go.drugbank.com/drugs/DB16502
    Investigational

    Additionally, ATI-450 was studied in a terminated trial (NCT05511519) to treat patients with psoriatic arthritis. … Zunsemetinib is being investigated in a new clinical trial (NCT06374459) for the treatment of hormone receptor-positive and HER2-negative metastatic breast cancer with bone metastasis.

  4. Drug

    MLN3897

    go.drugbank.com/drugs/DB06505
    Experimental

    MLN3897, a novel CCR1 inhibitor, disrupts osteoclast formation and blocks the interaction between multiple myeloma cells and osteoclasts.

  5. Drug

    Cystic fibrosis transmembrane conductance regulator

    go.drugbank.com/drugs/DB15180
    Investigational

    Cystic fibrosis transmembrane conductance regulator is under investigation in clinical trial NCT00004806 (Phase I Study of Liposome-Mediated Gene Transfer in Patients With Cystic Fibrosis).

    Categories: Ion Pumps, Ion Channels
  6. Drug

    Bexotegrast

    go.drugbank.com/drugs/DB16515
    Investigational

    In addition, the compound is also currently in Phase 2a trials (NCT04565249) for the treatment of COVID-19 related acute respiratory distress syndrome[L31713]. … The compound was granted orphan drug designation by the US FDA in August 2018 for treatment of IPF, and Pliant Therapeutics recently raised $100 million in Series C financing to support further clinical

  7. Drug

    Recombinant human plasma gelsolin

    go.drugbank.com/drugs/DB15746
    Investigational

    Plasma gelsolin (pGSN) is a protein found in the blood of healthy individuals which scavenges compounds left over from damaged tissues.

  8. Drug

    Androstenedione

    go.drugbank.com/drugs/DB01536
    IllicitInvestigational

    A delta-4 C19 steroid that is produced not only in the testis, but also in the ovary and the adrenal cortex. … Depending on the tissue type, androstenedione can serve as a precursor to testosterone as well as estrone and estradiol.

  9. Drug

    Arundic acid

    go.drugbank.com/drugs/DB05343
    Investigational

    Arundic acid has been investigated for the treatment of Amyotrophic Lateral Sclerosis (ALS).

  10. Drug

    Doxofylline

    go.drugbank.com/drugs/DB09273
    Investigational

    Doxofylline is a methylxanthine derivative with the presence of a dioxolane group in position 7. … As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with significantly fewer side effects in animal and human studies.