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EpiVacCorona
go.drugbank.com/drugs/DB16439InvestigationalIt is currently being tested in Phase I/II clinical trials for safety and immunogenicity (NCT04527575)[L30608, L30613].
INM005
go.drugbank.com/drugs/DB16499InvestigationalIt was studied for pharmacokinetics, efficacy, and safety in a completed trial (NCT04494984).
Luveltamab tazevibulin
go.drugbank.com/drugs/DB17563Investigational[A257414] It is under investigation in clinical trial NCT05200364 (A Study of STRO-002, an Anti-folate Receptor Alpha Antibody Drug Conjugate, in Combination With Bevacizumab in Epithelial Ovarian Cancer
Maropitant
go.drugbank.com/drugs/DB11427ExperimentalVet approvedIt was approved by the FDA in 2007 for use in dogs, and more recently has also been approved for use in cats.
2-Methoxyestradiol
go.drugbank.com/drugs/DB02342InvestigationalIt has undergone Phase 1 clinical trials against breast cancers and preclinical studies suggest that 2ME2 could also be effective against inflammatory diseases such as rheumatoid arthritis.
Pyruvaldehyde
go.drugbank.com/drugs/DB03587ExperimentalIt has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals. [PubChem]
NOV-002
go.drugbank.com/drugs/DB05393InvestigationalIt has been administered to over 10,000 patients, demonstrating clinical efficacy and excellent safety data.
3-amino-5-phenylpentane
go.drugbank.com/drugs/DB02869ExperimentalThese are compounds containing a phenylpropylamine moiety, which consists of a phenyl group substituted at the third carbon by a propan-1-amine. 3-amino-5-phenylpentane targets the proteins cathepsin K
Nebicapone
go.drugbank.com/drugs/DB14849InvestigationalNebicapone is under investigation in clinical trial NCT03097211 (Effect of BIA 6-512 at Steady-state on the Levodopa Pharmacokinetics With a Single-dose of Levodopa/Benserazide 200/50 mg or With a Single-dose
NTLA-2002
go.drugbank.com/drugs/DB17597InvestigationalIt is an investigational therapy designed to knock out the target gene kallikrein B1 (KLKB1) to reduce plasma kallikrein activity, thereby preventing hereditary angioedema attacks.[L45738]