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Ibritumomab tiuxetan
go.drugbank.com/drugs/DB00078ApprovedIndium or yttrium conjugated murine IgG1 kappa monoclonal antibody directed against the CD20 antigen, which is found on the surface of normal and malignant B lymphocytes. … Ibritumomab is produced in Chinese hamster ovary cells and is composed of two murine gamma 1 heavy chains of 445 amino acids each and two kappa light chains of 213 amino acids each.
Categories: Lymphoma, B-CellProducts: ZEVAMAB®NOX-100
go.drugbank.com/drugs/DB05799InvestigationalNOX-100 is the first in a series of proprietary NO neutralizing compounds Medinox is developing to bind and inactivate NO, a simple gas molecule that is a key biological messenger in the body. … NOX-100 is the new nitric oxide (NO) neutralizing agent being developed by San Diego-based Medinox -- demonstrated its effectiveness and potential as a therapeutic to treat hemorrhagic shock.
Sagopilone
go.drugbank.com/drugs/DB12391InvestigationalIt is a so-called fully synthetic epothilone and is the first such compound to be in clinical development to combat several forms of cancer. … Epothilones are 16-member ring macrolides with antimicrotubule activity that share a similar mechanism of action to the taxanes but have demonstrated potent antiproliferative activity in several different
Categories: Cytochrome P-450 CYP3A Inhibitors, Heterocyclic Compounds, 1-RingRhus Glabra Pollen
go.drugbank.com/drugs/DB13895ApprovedRhus Glabra Pollen pollen is the pollen of the Rhus Glabra Pollen plant. The pollen is mainly used in allergenic testing.
gamma-Aminobutyric acid
go.drugbank.com/drugs/DB02530ApprovedInvestigationalThe most common inhibitory neurotransmitter in the central nervous system.
Mixtures: Therabenzaprine-90-5Synonyms: γ-amino-n-butyric acid, 4-aminobutanoic acidAVR118
go.drugbank.com/drugs/DB04979InvestigationalAVR118 is being studied for the promise shown in its ability to mitigate the toxic side effects of other drugs (including those used to treat HIV infection and chemotherapeutic drugs employed in the treatment … This non-toxic peptide-nucleic acid, which to date has shown no indication of human toxicity, appears to stimulate the proinflammatory responses required to combat viral infections such as AIDS and human
UCB7362
go.drugbank.com/drugs/DB17096ExperimentalUCB7362 is an orally active plasmepsin X (PMX) inhibitor currently investigated for the treatment of malaria. … [A254232] UCB7362 is estimated to achieve a significant reduction in asexual blood-stage parasites.
Bopindolol
go.drugbank.com/drugs/DB08807ExperimentalBopindolol (INN) is an ester prodrug for the beta blocker [pindolol].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesEcabet
go.drugbank.com/drugs/DB05265InvestigationalEcabet is a prescription eye drop for the treatment of dry eye syndrome. … Ecabet represents a new class of molecules that increases the quantity and quality of mucin produced by conjunctival goblet cells and corneal epithelia.
Categories: Pepsin A, antagonists & inhibitors, Compounds used in a research, industrial, or household settingOxilofrine
go.drugbank.com/drugs/DB11610ApprovedOxilofrine is used in combination with [DB11609] as an antitussive. It is currently marketed in Canada by Valeant under the tradename Cophylac.
Synonyms: 4-HMP, 4-hydroxyephedrine