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Muplestim
go.drugbank.com/drugs/DB12431InvestigationalMuplestim is under investigation in clinical trial NCT00002258 (A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL
Azemiglitazone
go.drugbank.com/drugs/DB16028InvestigationalAzemiglitazone is under investigation in clinical trial NCT01280695 (A Randomized, Double-blind, Comparator- and Placebo-controlled, Multiple-dose Study to Evaluate the Safety, Tolerability and Efficacy
BMN-351
go.drugbank.com/drugs/DB18186InvestigationalBMN-351 is a fully modified 18-mer oligonucleotide with a TEG modification at its 5' end that binds to exon 51 of dystrophin pre-mRNA.
Zosurabalpin
go.drugbank.com/drugs/DB21539InvestigationalZosurabalpin is under investigation in clinical trial NCT05614895 (A Study to Investigate the Pharmacokinetics of RO7223280 in Critically Ill Participants With Bacterial Infections).
Sodium sulfide
go.drugbank.com/drugs/DB11159ApprovedInterestingly, sodium sulfide was shown to have some cardioprotective role against cardiac ischemia or reperfusion injury, as well as protect lungs against ventilator-induced lung injury [A27275].
Lumiliximab
go.drugbank.com/drugs/DB06162InvestigationalResults published from the CLL clinical trial failed to meet primary endpoints.
Trodusquemine
go.drugbank.com/drugs/DB06333InvestigationalIt has demonstrated the ability to stimulate regeneration of heart and multiple other tissues in animal models [A176600].
AAV-AIPL
go.drugbank.com/drugs/DB17857ExperimentalDeveloped by MeiraGTx, it is being investigated for the treatment of inherited retinal dystrophy due to defects in _AIPL1_ gene.
Elsibucol
go.drugbank.com/drugs/DB05840ExperimentalAGI-1096 is a novel oral antioxidant and selective anti-inflammatory agent that is being developed to address the accelerated inflammation of grafted blood vessels, known as transplant arteritis, common