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Displaying results 4821 - 4830 of 10000 in total
  1. Drug

    Cyclandelate

    go.drugbank.com/drugs/DB04838
    ApprovedWithdrawn

    Cyclandelate is not approved for use in the U.S. or Canada, but is approved in various European countries. … A direct-acting smooth muscle relaxant used to dilate blood vessels. It may cause gastrointestinal distress and tachycardia.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  2. Drug

    Etidocaine

    go.drugbank.com/drugs/DB08987
    Approved

    Etidocaine is marketed under the name Duranest. It is an injectable local anesthetic during surgery, labor, and delivery. … Etidocaine has a long duration of activity, but has the main disadvantage of increased bleeding during oral surgery.

  3. Drug

    Parecoxib

    go.drugbank.com/drugs/DB08439
    ApprovedInvestigational

    Parecoxib is a water-soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union. … Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx).

    Synonyms: N-((p-(5-methyl-3-phenyl-4-isoxazolyl)phenyl)sulfonyl)propionamideCategories: COX-2 Inhibitors, Cytochrome P-450 Substrates
  4. Drug

    DG041

    go.drugbank.com/drugs/DB05027
    Experimental

    EP3 is a target that associates with increased risk of various vascular diseases. … DG041 is a novel, first-in-class, orally-administered small molecule developmented for the prevention of arterial thrombosis and its complications.

  5. Drug

    Cintredekin besudotox

    go.drugbank.com/drugs/DB05305
    Investigational

    Cintredekin besudotox is made from a human protein, Interleukin 13 (IL13), linked to a bacterial toxin, _Pseudomonas exotoxin_ (PE). The IL13 portion binds to receptors on the tumor. … Cintredekin besudotox has been developed as a specific tumor-targeting agent, which is administered by positive-pressure convection-enhanced delivery (CED) directly to brain tissue at risk for residual

  6. Drug

    Paclitaxel docosahexaenoic acid

    go.drugbank.com/drugs/DB05297
    Investigational

    A combination of [docosahexaenoic Acid] (a natural fatty acid) and [paclitaxel] (an anticancer drug) being studied in the treatment of cancer. It is a type of mitotic inhibitor.

    Synonyms: Paclitaxel 2'-(all-cis-4,7,10,13,16,19-docosahexaenoate)
  7. Drug

    Chaetomium globosum

    go.drugbank.com/drugs/DB10430
    Approved

    Chaetomium globosum is a fungus which can provoke allergic reactions. Chaetomium globosum extract is used in allergenic testing.

    Mixtures: A Mold Mixture, A Mold Mixture
  8. Drug

    Cladosporium sphaerospermum

    go.drugbank.com/drugs/DB10432
    Approved

    Cladosporium sphaerospermum is a fungus which can provoke allergic reactions. Cladosporium sphaerospermum extract is used in allergenic testing.

    Mixtures: Mold Mix 3, Mold Mix 3
  9. Drug

    Ustilago tritici

    go.drugbank.com/drugs/DB10444
    Approved

    Ustilago tritici is a fungus which can provoke allergic reactions. Ustilago tritici extract is used in allergenic testing.

  10. Drug

    Trichophyton mentagrophytes

    go.drugbank.com/drugs/DB10446
    Approved

    Trichophyton mentagrophytes is a fungus which can provoke allergic reactions. Trichophyton mentagrophytes extract is used in allergenic testing.

    Mixtures: Mold Mix C, Mold Mix C