Parecoxib

DB08439ApprovedInvestigationalSmall moleculeAnti-Inflammatory Agents, Non-SteroidalCyclooxygenase Inhibitors

Parecoxib is a selective COX-2 inhibitor and NSAID used for the short-term management of perioperative pain. Parecoxib is a water-soluble and injectable prodrug of valdecoxib.

Chemical structure of Parecoxib
Mechanism
Curator reviewed
Primary indication
Used for short term perioperative pain control.Curator reviewed · 1 structured indication
Formula / weight
C19H18N2O4S · 370.422 g/mol (avg)
First approval
European Union, 2016
Code names
SC-69124
Brand names
  • Dynastat

Resolves to

Compound
UNII9TUW81Y3CECAS198470-84-7ChEMBLCHEMBL1206690ChEBI73038PubChem119828KEGGD02709
Clinical / RWD
RxNorm279950ATCM01AH04PharmGKBPA166049193
Structure
InChIKeyTZRHLKRLEZJVIJ-UHFFFAOYSA-NSMILESCCC(=O)NS(=O)(=O)C1=CC=C(C=C1)C1=C(C)ON=C1C1=CC=CC=C1
Targets
P35354PTGS2P02788LTF

What you can answer from here — as of September 23, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
1,618Drug interactionsStructured to mechanism, not free text
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60Clinical trialsPhase, status and sponsor resolved per trial
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1Structured indicationCondition, population, route and combination as fields, not prose
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13ContraindicationsEach with its own population and attribute set
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44Marketed productsAcross 8 countries and 10 labellers
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1ATC codeIncluding every combination product, plus 21 drug categories
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13+ReferencesStructured and connected to the statements they support
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