Search
Brilaroxazine
go.drugbank.com/drugs/DB09226InvestigationalBrilaroxazine (RP5063) is an investigational atypical antipsychotic which is under development by Reviva Pharmaceuticals for the treatment of schizophrenia and schizoaffective disorder. … As of May 2015, it is in phase III clinical trials for schizophrenia.
Synonyms: 6-(4-(4-(2,3-Dichlorophenyl)-piperazin-1-yl)-butoxy)-2H-benzo(b)(1,4)oxazin-3(4H)-oneCategories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2C Receptor Antagonistsgamma-Aminobutyric acid
go.drugbank.com/drugs/DB02530ApprovedInvestigationalThe most common inhibitory neurotransmitter in the central nervous system.
Synonyms: γ-amino-n-butyric acid, 4-aminobutanoic acidMixtures: Therabenzaprine-90-5GR270773
go.drugbank.com/drugs/DB06427InvestigationalGR270773, was investigated in two clinical trials for its potential to treat sepsis: NCT00158769 (completed, comparing the effects of infusion between healthy adults and those with damaged livers) and … NCT00089986 (completed with results, treatment of suspected or confirmed gram-negative severe sepsis in adults, comparing GR270773 with a placebo).
CYP-001
go.drugbank.com/drugs/DB15739InvestigationalCYP-001 is a mesenchymoangioblast (MCA)-derived mesenchymal stem cell (MSC) therapy that originates from the mesoderm. … These cells have advantage over other MSCs because a large amount can be obtained from a single healthy blood donor, negating the risks from donor-and expansion dependent variability.
Besifovir dipivoxil
go.drugbank.com/drugs/DB05020InvestigationalBesifovir dipivoxil is a small-molecule orally available inhibitor of the HBV polymerase. The HBV polymerase is the enzyme that catalyzes the production of new RNA from the existing strand of RNA. … Besifovir dipivoxil is believed to inhibit viral proliferation by interrupting the replicating machinery of the virus.
Categories: Heterocyclic Compounds, 2-RingAVR118
go.drugbank.com/drugs/DB04979InvestigationalAVR118 is being studied for the promise shown in its ability to mitigate the toxic side effects of other drugs (including those used to treat HIV infection and chemotherapeutic drugs employed in the treatment … This non-toxic peptide-nucleic acid, which to date has shown no indication of human toxicity, appears to stimulate the proinflammatory responses required to combat viral infections such as AIDS and human
Tyropanoic acid
go.drugbank.com/drugs/DB09340ApprovedThe molecule contains three heavy iodine atoms which obstruct X-rays in the same way as the calcium in bones, which results in a visible image [L1608]. … Tyropanoic acid is a radiocontrast agent used in cholecystography, the X-ray diagnosis of gallstones under the trade names include Bilopaque, Lumopaque, Tyropaque, and Bilopac.
Categories: X-Ray Contrast Media, Iodinated, Watersoluble, Hepatotropic X-Ray Contrast MediaAdPEDF
go.drugbank.com/drugs/DB05138ExperimentalAdPEDF is under development for the treatment of wet age-related macular degeneration (AMD). … It has been shown to rapidly elevate the intraocular AdPEDF protein levels in the eye, inhibit abnormal blood vessel growth, and cause abnormal blood vessels to regress while protecting the eye’s photoreceptors
Rhus Glabra Pollen
go.drugbank.com/drugs/DB13895ApprovedRhus Glabra Pollen pollen is the pollen of the Rhus Glabra Pollen plant. The pollen is mainly used in allergenic testing.
Halofuginone
go.drugbank.com/drugs/DB04866InvestigationalVet approvedCollgard Biopharmaceuticals is developing halofuginone for the treatment of scleroderma and received orphan drug designation from the U.S. Food and Drug Administration in March, 2000. … Halofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 (MMP-2) gene expression.
Synonyms: (+/-)-trans-7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidyl)-acetonyl)-4(3H)-quinazolinoneCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring