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Sparfosic acid
go.drugbank.com/drugs/DB03459ExperimentalThese are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen atom.
Ulotaront
go.drugbank.com/drugs/DB15665Investigational[L12891] An initial clinical study has shown this drug may be effective against both positive and negative symptoms of schizophrenia. … Unlike other drugs used for this condition, SEP-363856 does not bind to the dopamine D2 receptors, but exerts actions on the trace amine–associated receptor 1 (TAAR1) and 5-hydroxytryptamine type 1A (5
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesGuanosine
go.drugbank.com/drugs/DB02857InvestigationalGuanosine can be phosphorylated to become GMP (guanosine monophosphate), cGMP (cyclic guanosine monophosphate), GDP (guanosine diphosphate) and GTP (guanosine triphosphate) which are factors in signal
Synonyms: 9-β-D-ribofuranosyl-guanine, Guanine-9-β-D-ribofuranosideUmeclidinium
go.drugbank.com/drugs/DB09076ApprovedInvestigationalUmeclidinium is a long-acting muscarinic antagonist (LAMA) used as a maintenance treatment for symptoms of chronic obstructive pulmonary disease (COPD). COPD is a progressive obstructive lung disease characterized by shortness of breath,...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesLoracarbef
go.drugbank.com/drugs/DB00447ApprovedWithdrawnLoracarbef is a carbacephem antibiotic sometimes grouped together with the second-generation cephalosporin antibiotics. It is marketed under the trade name Lorabid.
Selexipag
go.drugbank.com/drugs/DB11362ApprovedInvestigationalSelexipag was approved by the United States FDA on December 22, 2015 for the treatment of pulmonary arterial hypertension (PAH) to delay disease progression and reduce risk of hospitalization. PAH is a relatively rare disease with usuall...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesPlecanatide
go.drugbank.com/drugs/DB13170ApprovedInvestigationalPlecanatide is a drug approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation (CIC). It should not be used in children less than six years of age, and should be avoided in patients six years to 18 years o...
WP-1122
go.drugbank.com/drugs/DB17192InvestigationalWP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). It was granted FDA orphan designation for the treatment of glioblastoma multiforme.[L47361]
Synonyms: an acetic acid diester of 2-deoxy-D-glucose, 3,6-di-O-acetyl-2-deoxy-D-glucopyranoseParathyroid hormone
go.drugbank.com/drugs/DB05829ApprovedInvestigationalAvailable as Preotact, it is an identical form of human recombinant hormome which produced as a fusion protein undergoeing post-translational processing involving the cleavage of the OmpA leader sequence