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Displaying results 4841 - 4850 of 10000 in total
  1. Drug

    Fleroxacin

    go.drugbank.com/drugs/DB04576
    Experimental

    Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase. Fleroxacin is not an inhibitor of CYP1A2.[A39048]

    Categories: 4-Quinolones, Heterocyclic Compounds, 2-Ring
  2. Drug

    Aldosterone

    go.drugbank.com/drugs/DB04630
    Investigational

    A hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.

    Synonyms: (11β)-11,21-dihydroxy-3,20-dioxopregn-4-en-18-al, 11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-alCategories: P-glycoprotein inducers, P-glycoprotein substrates
  3. Drug

    Carboxin

    go.drugbank.com/drugs/DB04657
    ApprovedWithdrawn

    A systemic agricultural fungicide and seed treatment agent.

    Synonyms: 5,6-Dihydro-2-methyl-N-phenyl-1,4-oxathiin-3-carboxamide, 2,3-Dihydro-5-carboxanilido-6-methyl-1,4-oxathiinCategories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household setting
  4. Drug

    Coumarin

    go.drugbank.com/drugs/DB04665
    Investigational

    Synonyms: 2H-1-benzopyran-2-one, 2H-benzo(b)pyran-2-oneCategories: Vitamin K Antagonists, Cytochrome P-450 Substrates
  5. Drug

    2-tert-butyl-9-fluoro-1,6-dihydrobenzo[h]imidazo[4,5-f]isoquinolin-7-one

    go.drugbank.com/drugs/DB04716
    Experimental

    Synonyms: 2-tert-butyl-9-fluoro-1,6-dihydrobenzo[h]imidazo[4,5-f]isoquinolin-7-one, CMP 6Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  6. Drug

    Gentamicin C1a

    go.drugbank.com/drugs/DB04729
    Experimental

    Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index
  7. Drug

    Sulfatide

    go.drugbank.com/drugs/DB04780
    Experimental

    Any of a class of cerebroside sulfuric esters, they are found largely in the medullated nerve fibers and may accumulate in metachromatic leukodystrophy.

    Synonyms: 2-hydroxytetracosanoyl sulfatide, 2-hydroxytetracosanoylgalactosylceramide sulfate
  8. Drug

    Zomepirac

    go.drugbank.com/drugs/DB04828
    ApprovedWithdrawn

    The manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983. … Zomepirac, formerly marketed as Zomax tablets, was associated with fatal and near-fatal anaphylactoid reactions.

    Synonyms: 5-(4-Chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic acidCategories: Non COX-2 selective NSAIDS, Cytochrome P-450 Substrates
  9. Drug

    Amineptine

    go.drugbank.com/drugs/DB04836
    ApprovedIllicitWithdrawn

    The Food and Drug Administration suspended the marketing authorisation for Survector in 1999 and France withdrew it from the market, however several developing countries continued to produce it up until 2005.

  10. Drug

    Debrisoquine

    go.drugbank.com/drugs/DB04840
    Approved

    It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. … They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.

    Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates