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Displaying results 4851 - 4860 of 8700 in total
  1. Drug

    Metoprolol

    go.drugbank.com/drugs/DB00264
    ApprovedInvestigational

    Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release. The possibility of the generation of these form...

    Categories: Antihypertensive Agents Indicated for Hypertension, Adrenergic beta-1 Receptor Antagonists
  2. Drug

    Apadenoson

    go.drugbank.com/drugs/DB05009
    Investigational

    Apadenoson is a selective A2a adenosine receptor agonist designed for use as a pharmacologic stress agent in cardiac perfusion imaging studies.

    Categories: Adenosine A receptor agonists, Adenosine A2 Receptor Agonists
  3. Drug

    Frovatriptan

    go.drugbank.com/drugs/DB00998
    Approved

    Frovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  4. Drug

    CZEN 002

    go.drugbank.com/drugs/DB05479
    Experimental

    A second focus was on the sequence Lys-Pro-Val (11-13) that is known to be important for antimicrobial activity. … This organism can invade tissues and produce fatal infections in individuals with compromised immune systems such as those suffering from HIV/AIDS or undergoing organ or bone transplants.

  5. Drug

    Taliglucerase alfa

    go.drugbank.com/drugs/DB08876
    Approved

    It was approved in 2012 and is marketed under the name Elelyso for use in patients with type 1 Gaucher's disease.

  6. Drug

    Carfentanil

    go.drugbank.com/drugs/DB01535
    IllicitInvestigationalVet approved

    Carfentanil is intended for large-animal use only as its extreme potency makes it inappropriate for use in humans. … Carfentanil or carfentanyl (Wildnil) is an analogue of the popular synthetic opioid analgesic fentanyl, and is one of the most potent opioids known (also the most potent opioid used commercially).

  7. Drug

    Autogene cevumeran

    go.drugbank.com/drugs/DB17497
    Investigational

    Autogene cevumeran is an mRNA-based cancer vaccine targeting an unspecified amount of tumour-associated antigens. It is being investigated for cancers.

  8. Drug

    Salanersen

    go.drugbank.com/drugs/DB18418
    Investigational

    BIIB115 is an investigational antisense oligonucleotide in development for spinal muscular atrophy.

  9. Drug

    Zotarolimus

    go.drugbank.com/drugs/DB18761
    Investigational

    Zotarolimus is an immunosuppressant under investigation for use in drug-eluting stents.

  10. Drug

    Ketobemidone

    go.drugbank.com/drugs/DB06738
    Investigational

    This makes it useful for some types of pain that don't respond well to other opioids. … The most commonly cited equalisation ratio for analgesic doses is 25 mg of ketobemidone hydrobromide to 60 mg of morphine hydrochloride or sulfate and circa 8 mg of ketobemidone by injection.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Substrates