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Chloroquine
go.drugbank.com/drugs/DB00608ApprovedInvestigationalVet approved[A192432] **The FDA emergency use authorization for [hydroxychloroquine] and chloroquine in the treatment of COVID-19 was revoked on 15 June 2020. … [A191787] Chloroquine and its derivative [hydroxychloroquine] have since been repurposed for the treatment of a number of other conditions including HIV, systemic lupus erythematosus, and rheumatoid arthritis
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamineKanamycin
go.drugbank.com/drugs/DB01172ApprovedInvestigationalVet approvedWithdrawnKanamycin (also known as kanamycin A) is an aminoglycoside bacteriocidal antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections.
Synonyms: Kanamycin A, 4,6-diamino-2-hydroxy-1,3-cyclohexane 3,6'diamino-3,6'-dideoxydi-α-D-glucosideInternational brands: Kancin-LSodium iodide
go.drugbank.com/drugs/DB11119ApprovedInvestigationalSodium iodide is a source of iodine and can be administered as a supplement for total parenteral nutrition [L2065] but is more commonly used in veterinary medicine. … Sodium iodide is a water-soluble ionic compound with a crystal lattice.
Mixtures: De La Cruz Tincture of Iodine, FERTOMCIDINA UProducts: TAEK-PHT 123I-NAI (SODYUM İYODÜR) 37 MBQ/ML I.V. ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET, Micro IErdafitinib
go.drugbank.com/drugs/DB12147ApprovedInvestigationaltool kit to treat such a prevalent medical condition. … [L5956, L5959] At the same time, the FDA also approved the therascreen FGFR RGQ RT-PCR Kit (Qiagen) for utilization as a companion diagnostic with erdafitinib for selecting patients for the indicated therapy
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic IndexProducts: BALVERSA 5 MG FİLM KAPLI TABLET, 28 ADET, BALVERSA 3 MG FİLM KAPLI TABLET, 56 ADETAtomoxetine
go.drugbank.com/drugs/DB00289ApprovedInvestigationalMore recently, positron emission tomography (PET) imaging studies in rhesus monkeys have shown that atomoxetine also binds to the serotonin transporter (SERT),[A178111] and blocks the N-methyl-d-aspartate … (NMDA) receptor,[A18263] indicating a role for the glutamatergic system in the pathophysiology of ADHD.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesProducts: SETİNOX 5 MG KAPSÜL, 28 ADET, ATTENTHO ®10 MG CAPSULASFerrous glycine sulfate
go.drugbank.com/drugs/DB14501ApprovedProducts: FERRO SANOL DUODENAL 100 MG KAPSUL, 50 ADET, FERRO SANOL 40 MG KAPLI TABLET, 50 ADETZinc oxide
go.drugbank.com/drugs/DB09321ApprovedInvestigationalZinc oxide is an inorganic compound used in a number of manufacturing processes. … It is also widely used to treat a variety of other skin conditions, in products such as baby powder and barrier creams to treat diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments
Mixtures: Calcium Mg and Zn Capsules With Vitamin D, Esika Pro Instant Perfection 3 En 1 Face Refining Foundation SPF 25 Medio 5 - BeigeCategories: Compounds used in a research, industrial, or household settingDapsone
go.drugbank.com/drugs/DB00250ApprovedInvestigationalIt is also used with pyrimethamine in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8) … A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae.
Mixtures: Dapsone 6% / Niacinamide 2% / Spironolactone 5%, 011503 Dapsone 6% / Niacinamide 2% / Spironolactone 5%Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 InducersAtorvastatin
go.drugbank.com/drugs/DB01076ApprovedInvestigationalthe number of major cardiovascular events (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction in LDL without any significant side effects or risks. … More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid.
Mixtures: EZETIMIBE E ATORVASTATINA DOC, EZETIMIBE E ATORVASTATINA DOCCategories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitorsManidipine
go.drugbank.com/drugs/DB09238ApprovedInvestigationalWithdrawnManidipine (INN) is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive. … It is selective for vasculature and does not produce effects on the heart at clinically relevant dosages.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesProducts: MANIDIPINA EG, IPERTEN 20 MG TABLET, 28 ADET