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Resmetirom
go.drugbank.com/drugs/DB12914ApprovedInvestigationalResmetirom is a thyroid hormone receptor-beta (THR-beta) agonist. On March 14, 2024, it was approved by the FDA as the first treatment of liver fibrosis due to noncirrhotic non-alcoholic steatohepatitis (NASH), which is a form of non-alc...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsGallopamil
go.drugbank.com/drugs/DB12923InvestigationalGallopamil has been used in trials studying the treatment of Asthma.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesCafedrine
go.drugbank.com/drugs/DB12926InvestigationalCafedrine is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesTheodrenaline
go.drugbank.com/drugs/DB12927InvestigationalTheodrenaline is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesTirilazad
go.drugbank.com/drugs/DB13050InvestigationalTirilazad has been used in trials studying the treatment of Spinal Cord Injury.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesNorflurane
go.drugbank.com/drugs/DB13116ApprovedInvestigationalWithdrawnNorflurane is under investigation in clinical trial NCT01673061 (Vapocoolant Spray for Numbing Small Boils Before Incision and Drainage).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 SubstratesArtemisinin
go.drugbank.com/drugs/DB13132InvestigationalArtemisinin has been used in trials studying the treatment of Schizophrenia, Malaria, Falciparum, and Plasmodium Falciparum.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersEsculin
go.drugbank.com/drugs/DB13155ApprovedThese are carbohydrate derivatives in which a sugar group is bonded through its anmoeric carbonA to another group via a C-, S-,N-,O-, or Se- glycosidic bond. … Vitamin C2 is generally considered a bioflavanoid, related to vitamin P esculin is a glucoside that naturally occurs in the horse chestnut (Aesculus hippocastanum), California Buckeye (Aesculus californica
Horse chestnut
go.drugbank.com/drugs/DB13195InvestigationalHorse chestnut is a flowering plant commonly referred to as Aesculus hippocastanum. Unprocessed horse chestnut seeds contain a toxin called esculin (also spelled aesculin) that increases the risk of bleeding due to anticoagulant actions....
Mixtures: REPARİL-GEL N %1 + %5 JEL, 50 GProducts: Venostatin N Ointment 42mg/gmPrednylidene
go.drugbank.com/drugs/DB13208ExperimentalPrednylidene is an experimental systemic glucocorticoid.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers