Search

OSI-7836

It is also more active than ara-C (another clinically used nucleoside analog) in all nine models and more active than either paclitaxel or cisplatin in the two lung xenograft models tested. … This drug shows no unexpected toxicities; those observed appeared to be similar to other nucleoside agents.

Triazavirin

[L12087] Given the similarities between SARS-CoV-2 and H5N1, health officials are investigating Triazavirin as an option to combat SARS-CoV-2, the coronavirus responsible for COVID-19.[A191625] … [A191709,A191625,A191916] It appears that Triazavirin has shown promise in reducing influenza disease severity and associated complications.

WL-1002

WL-1002 is developed by Winston Laboratories which is a topical cream formulation of 075% zucapaicin (also known as civamide), for the treatment of pain due to osteoarthritis.

Diphemanil

Guanosine tetraphosphate

Two phosphate groups are esterified to the sugar moiety in the 5' position and the other two in the 2' or 3' position. … Guanosine tetraphosphate is a guanine nucleotide containing four phosphate groups.

Clomocycline

Clomocycline is a tetracycline used to treat bacterial infections.

Mephenesin

Mephenesin is a synthetic cresol glyceryl ether which produces transient muscle relaxation and paralysis via central nervous system depression [A32760]. It first entered use in the 1950s.

Amolimogene bepiplasmid

Amolimogene is an investigational therapeutic designed to specifically augment the body's defensive response to human papillomavirus (HPV). … Amolimogene was biologically engineered as a targeted therapy for the treatment of cervical dysplasia.

Citrus bioflavonoids

ACA 125

To create ACA-125, a hybridoma cell was adapted to serum-free medium and antibody was produced in a hollow fiber cell culture system. Positive clinical results are now being reported. … ACA-125 mimics the tumor-associated antigen CA-125, which can be detected in about 80% of ovarian carcinomas.