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Asimadoline
go.drugbank.com/drugs/DB05104InvestigationalIt has shown encouraging clinical efficacy for the treatment of IBS in a barostat study in IBS patients and has the potential for treating other gastrointestinal diseases. … Asimadoline is a proprietary small molecule therapeutic, originally discovered by Merck KGaA of Darmstadt, Germany. Asimadoline was originally developed to treat peripheral pain such as arthritis.
Garlic
go.drugbank.com/drugs/DB10532ApprovedNutraceuticalGarlic allergenic extract is used in allergenic testing.
Mixtures: BiO-LiFE Anti-FR+Selenium TabletsCategories: Non-Standardized Food Allergenic ExtractDiprenorphine
go.drugbank.com/drugs/DB01548IllicitInvestigationalVet approvedA narcotic antagonist similar in action to naloxone. It is used to remobilize animals after etorphine neuroleptanalgesia and is considered a specific antagonist to etorphine. [PubChem]
Categories: Heterocyclic Compounds with 4 or More RingsLufotrelvir
go.drugbank.com/drugs/DB16514InvestigationalNow, it is being tested regarding the novel SARS-CoV-2 virus, including studies in conjunction with [Remdesivir] to treat COVID-19 infection; in vitro data showed synergistic effects on articles published … on preprint servers[L31733, L31125].
Categories: Experimental Unapproved Treatments for COVID-19Remikiren
go.drugbank.com/drugs/DB00212ExperimentalRemikiren is an orally active, high specificity renin inhibitor.
Categories: Agents Acting on the Renin-Angiotensin SystemElacytarabine
go.drugbank.com/drugs/DB05494InvestigationalElacytarabine is designed to overcome this limitation and has shown considerable uptake in solid tumour cells. … Elacytarabine is a fatty acid derivative of [cytarabine], an approved cytotoxic cancer drug. Cytarabine has limitations such as minimal uptake in solid tumours and is only used to treat leukaemia.
Estrone
go.drugbank.com/drugs/DB00655ApprovedEstrone, one of the major mammalian estrogens, is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone. It is produced in vivo from androstenedione or from testosterone via estradiol. … It is produced primarily in the ovaries, placenta, and in peripheral tissues (especially adipose tissue) through conversion of adrostenedione.
Avizakimab
go.drugbank.com/drugs/DB18842InvestigationalAvizakimab is under investigation in clinical trial NCT03371251 (Study of BOS161721 in Systemic Lupus Erythematosus (SLE) Patients on a Background of Limited Standard of Care).
Hydroxycitronellal
go.drugbank.com/drugs/DB14187ApprovedHydroxycitronellal is a synthetic fragrance that is widely used in many cosmetics and hygiene products such as deodorants, soaps, antiseptics, and other household items. … It has the smell of lilac, lily, and lily of the valley [A34269].