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ATP-dependent 6-phosphofructokinase, muscle type
go.drugbank.com/bio_entities/BE0012586TargetHumansCatalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
Synonyms: PFK-A, 6-phosphofructokinase type APhospholipase A1
go.drugbank.com/bio_entities/BE0002041TargetEscherichia coli (strain K12)Has broad substrate specificity including hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Strong expression leads to outer membrane breakdown and cell death; is dormant ...
Synonyms: DR-phospholipase A, Outer membrane phospholipase AEnuresis
go.drugbank.com/conditions/DBCOND0018540Drugs: ImipramineSynonyms: Enuresis not due to a substance or known physiological conditionTadalafil
go.drugbank.com/drugs/DB00820ApprovedInvestigationalIn contrast to other PDE5 inhibitors like [sildenafil], tadalafil has greater selectivity for PDE5 and a longer half-life which has made it a more suitable option for chronic once-daily dosing in the treatment … Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy.
Mixtures: TADA PLUS 30/20 MG FILM KAPLI TABLET ,4 ADET, TADA PLUS 30/20 MG FILM KAPLI TABLET ,8 ADETCategories: Drugs Used in Erectile Dysfunction, Drugs Used in Benign Prostatic HypertrophyInterferon alpha-2
go.drugbank.com/bio_entities/BE0003450TargetHumansProduced by macrophages, IFN-alpha have antiviral activities
Synonyms: LeIF A, Interferon alpha-ALinezolid
go.drugbank.com/drugs/DB00601ApprovedInvestigational[A233425] A second member of this class, [tedizolid], was approved by the FDA in 2014 and is considered generally more effective and tolerable than its predecessor. … Linezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Heterocyclic Compounds, 1-RingSynonyms: N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamideValsartan
go.drugbank.com/drugs/DB00177ApprovedInvestigationalARBs such as valsartan have been shown in a number of large-scale clinical outcomes trials to improve cardiovascular outcomes including reducing risk of myocardial infarction, stroke, the progression of … In particular, heart failure is associated with chronic activation of RAAS, leading to inappropriate fluid retention, vasoconstriction, and ultimately a further decline in left ventricular function.
Mixtures: CARDIK® A 80/5, CARDIK® A 80/5Categories: Angiotensin 2 Receptor Blocker, Cytochrome P-450 SubstratesIrbesartan
go.drugbank.com/drugs/DB01029ApprovedInvestigational[L7456,L7459] It can also be used as part of a combination product with [hydrochlorothiazide] for patients not well controlled or not expected to be well controlled on monotherapy. … [L7459] Unlike angiotensin converting enzyme inhibitors, ARBs are not associated with a dry cough.[L7456,L7459] Irbesartan was granted FDA approval on 30 September 1997.[L7456,L7459]
Mixtures: IRBEPREX A® 300/10 MG TABLETAS, IRBEPREX A® 300/10 MG TABLETASCategories: Angiotensin 2 Receptor Blocker, Cytochrome P-450 SubstratesDe Novo Triacylglycerol Biosynthesis TG(10:0/a-13:0/a-13:0)
smpdb.ca/view/SMP0031934MetabolicA triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. … Last, the enzyme diacylglycerol O-acyltransferase synthesizes triacylglycerol from diacylglycerol and a fatty acyl-CoA.
De Novo Triacylglycerol Biosynthesis TG(10:0/a-13:0/a-25:0)
smpdb.ca/view/SMP0031938MetabolicA triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. … Last, the enzyme diacylglycerol O-acyltransferase synthesizes triacylglycerol from diacylglycerol and a fatty acyl-CoA.