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KB3305
go.drugbank.com/drugs/DB06349ExperimentalKB3305 is an investigational liver selective antagonist for the glucocorticoid receptor, developed by Karo Bio for the treatment of Type 2 Diabetes.
OMS906
go.drugbank.com/drugs/DB17722InvestigationalOMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease-3 (MASP-3) currently being developed by Omeros.
Seliforant
go.drugbank.com/drugs/DB15220InvestigationalSeliforant is under investigation in clinical trial NCT01260753 (Proof of Activity Study of UR-63325 in Allergic Rhinitis Induced by Nasal Challenge).
Cephalothin Group
go.drugbank.com/drugs/DB03450ExperimentalThis compound belongs to the 1,3-thiazines. … This substance is known to target beta-lactamase Toho-1 and D-alanyl-D-alanine carboxypeptidase.
Inolimomab
go.drugbank.com/drugs/DB15628InvestigationalInolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease. … It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a higher risk of infections.[A241385]
Enalaprilat
go.drugbank.com/drugs/DB09477ApprovedInvestigationalEnalaprilat was originally created to overcome the limitations of the first ACE inhibitor, captopril, which had numerous side effects and left a metallic taste in the mouth. … Removal of the problematic thiol group from captopril resulted in enalaprilat, which was then modified further with an ester to create the orally available pro-drug enalapril.
Methyprylon
go.drugbank.com/drugs/DB01107ApprovedIllicitWithdrawnMethyprylon was withdrawn from the U.S. market in June 1965 and the Canadian market in September 1990 due to adverse events.
PRLX 93936
go.drugbank.com/drugs/DB06098InvestigationalPRLX 93936 is selectively toxic to cancer cells.