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Lefitolimod
go.drugbank.com/drugs/DB15061InvestigationalLefitolimod is under investigation in clinical trial NCT03837756 (Combining TLR9 Agonist With bNAbs for Reservoir Reduction and Immunological Control of HIV).
FET F-18
go.drugbank.com/drugs/DB15405InvestigationalFET F-18 is under investigation in clinical trial NCT01756352 (FET-PET for Evaluation of Response of Recurrent GBM to Avastin).
ISIS 104838
go.drugbank.com/drugs/DB16201InvestigationalISIS 104838 is under investigation in clinical trial NCT00048321 (ISIS 104838, an Inhibitor of Tumor Necrosis Factor, for Active Rheumatoid Arthritis).
Dalcinonacog alfa
go.drugbank.com/drugs/DB17707InvestigationalIt is being investigated for the treatment of hemophilia B.[A259058]
GT-AS
go.drugbank.com/drugs/DB17883ExperimentalGT-AS recombinant adeno-associated virus serotype 9 vector containing the transgene UBE3A encoding for ubiquitin protein ligase E3A/E6-AP.
OTOF-GT
go.drugbank.com/drugs/DB18129InvestigationalOTOF-GT is a dual vector AAV gene therapy being investigated for the restoration of hearing loss associated with otoferlin deficiency.
TTX-MC138
go.drugbank.com/drugs/DB18628Investigational[L48335] It is under investigation for the treatment of various metastatic cancers.
Rilvegostomig
go.drugbank.com/drugs/DB18991InvestigationalRilvegostomig is under investigation in clinical trial NCT06109779 (Rilvegostomig + Chemotherapy as Adjuvant Therapy for Biliary Tract Cancer After Resection (Artemide-biliary01)).
Zelquistinel
go.drugbank.com/drugs/DB19336InvestigationalZelquistinel is under investigation in clinical trial NCT06547489 (GATE-251 or Placebo for the Reduction of Symptoms of Major Depressive Disorder).
Ezurpimtrostat
go.drugbank.com/drugs/DB16458InvestigationalCategories: Experimental Unapproved Treatments for COVID-19