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XL784
go.drugbank.com/drugs/DB04991InvestigationalXL784 is a potent inhibitor of the ADAM-10 metalloprotease enzyme, a target of significant interest because of its important role in blood vessel formation and cell proliferation.
Mequitazine
go.drugbank.com/drugs/DB01071InvestigationalMequitazine is a histamine H1 antagonist (antihistamine). … It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract.
Polydatin
go.drugbank.com/drugs/DB11263ApprovedIt is shown to mediate a cytotoxic action on colorectal cancer cells by inducing cell arrest and apoptosis [A27229]. … Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline structure.
Synonyms: Polydatin (E)-isomerRice bran oil
go.drugbank.com/drugs/DB11293ApprovedInvestigationalRice bran oil is classified as an indirect additive used in food contact substances by the FDA.
Dehydroascorbic acid
go.drugbank.com/drugs/DB08830ExperimentalCurrently dehydroascorbic acid is an experimental drug with no known approved indications. … Dehydroascorbic acid as well as ascorbic acid are both termed Vitamin C, but the latter is the main form found in humans.
Synonyms: L-dehydroascorbate, dehydro-L-ascorbic acidPirlindole
go.drugbank.com/drugs/DB09244ExperimentalThis drug is classified as a reversible inhibitor of monoamine oxidase A enzyme (also known as a RIMA drug). It was developed and is currently used as an antidepressant in Russia. … Pirlindole is a selective, reversible inhibitor of monoamine oxidase (MAO) subtype A (MAO-A) that is approved in several European and non-European countries for the treatment of major depression.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesFidexaban
go.drugbank.com/drugs/DB19562ExperimentalFidexaban is a small molecule drug. The usage of the INN stem '-xaban' in the name indicates that Fidexaban is a blood coagulation factor XA inhibitor, antithrombotic. … Fidexaban has a monoisotopic molecular weight of 526.18 Da.
Hymecromone
go.drugbank.com/drugs/DB07118InvestigationalCategories: Compounds used in a research, industrial, or household settingMotretinide
go.drugbank.com/drugs/DB13368ExperimentalCategories: Vitamin A, Retinoids for Topical Use in Acne