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Glypromate
go.drugbank.com/drugs/DB05633ExperimentalIn December 2008, the company discontinued further development of the drug after it failed to show an observable effect.
ICA-105665
go.drugbank.com/drugs/DB06089InvestigationalIt is a novel opener of the KCNQ ion channel which in preclinical studies has demonstrated a broad spectrum of activity in models of epilepsy.
RO7284755
go.drugbank.com/drugs/DB17527InvestigationalRO7284755 is an investigational cancer drug: it is a PD-1-targeted IL-2 variant antibody fusion protein.
Sonpiretigene isteparvovec
go.drugbank.com/drugs/DB17844InvestigationalDeveloped by Nanoscope Therapeutics, it is being investigated for vision restoration in advanced retinitis pigmentosa (RP).
scAAV9.U7.ACCA
go.drugbank.com/drugs/DB18582InvestigationalDeveloped by Nationwide Children’s Hospital, it is being investigated for the treatment of Duchenne muscular dystrophy.
Recombinant Bacterial ACE2 Receptors-like Enzyme
go.drugbank.com/drugs/DB15741InvestigationalIt is being investigated for treating hypertension, myocardial fibrosis, and cardiac dysfunction.
BACTEK-R
go.drugbank.com/drugs/DB16526InvestigationalThough studies have shown that it reduces the rate of infections in recurrent respiratory tract infections (RRTIs), the complete mechanisms are not fully understood.
Clocapramine
go.drugbank.com/drugs/DB09003ExperimentalClocapramine has been implicated in at least one strange death, including a suicide.
Cardarine
go.drugbank.com/drugs/DB05416InvestigationalCardarine (GW-501516) is a peroxisome proliferator-activator receptor-delta agonist for the potential treatment of dyslipidemia. Cardarine has been investigated for the treatment of Obesity, Lipid Disorders, and Cardiovascular Disease.
Zunsemetinib
go.drugbank.com/drugs/DB16502InvestigationalATI-450 was under investigation in clinical trials (NCT05279417 and NCT05216224) for treating patients with rheumatoid arthritis and hidradenitis suppurativa, respectively. Additionally, ATI-450 was studied in a terminated trial (NCT0551...