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Isoaminile
go.drugbank.com/drugs/DB08944ApprovedWithdrawnIsoaminile, an antitussive drug with a structure similar to methadone, is also an anticholinergic with both antimuscarinic and antinicotinic properties.
CNS-5161
go.drugbank.com/drugs/DB05824ExperimentalCNS 5161 is a blocker of the NMDA ion channel and has completed Phase IIa proof of concept clinical trials as a novel compound for the treatment of neuropathic pain.
Phenothrin
go.drugbank.com/drugs/DB13717InvestigationalCategories: Compounds used in a research, industrial, or household settingCarfentanil
go.drugbank.com/drugs/DB01535IllicitInvestigationalVet approvedCarfentanil was first synthesized in 1974 by a team of chemists at Janssen Pharmaceutica which included Paul Janssen. … Carfentanil is intended for large-animal use only as its extreme potency makes it inappropriate for use in humans.
Triazavirin
go.drugbank.com/drugs/DB15622Investigational[A191709,A191625,A191916] It appears that Triazavirin has shown promise in reducing influenza disease severity and associated complications. … Triazavirin is a guanine nucleotide analog antiviral originally developed in Russia that has shown efficacy against influenza A and B, including the H5N1 strain.
Resiquimod
go.drugbank.com/drugs/DB06530InvestigationalA substance being studied in the treatment of some types of skin cancer. When put on the skin, resiquimod causes some immune cells to make certain chemicals that may help them kill tumor cells.
Galidesivir
go.drugbank.com/drugs/DB11676Investigational[A191451] In animal studies, galidesivir was effective in increasing the survival rates from infections caused by various pathogens, including Ebola, Marburg, Yellow Fever and Zika viruses. … Galidesivir is an adenosine analogue that has been investigated for use against Zaire Ebolavirus.
Sirna-027
go.drugbank.com/drugs/DB05896InvestigationalSirna-027 is a chemically modified short interfering RNA(siRNA) targeting Vascular Endothelial Growth Factor Receptor-1(VEGFR-1). VEGFR-1 is a key component of the clinically validated vascular endothelial growth factor (VEGF) pathway. S...
beta-Hydroxybutyric acid
go.drugbank.com/drugs/DB16506InvestigationalBeta-hydroxybutyrate is being studied in around 230 clinical trials, including NCT06351124 (recruiting for Crohn's disease), NCT05584371 (recruiting for safety and tolerability of exogenous ketosis), NCT04656236