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Ezetimibe
go.drugbank.com/drugs/DB00973ApprovedInvestigationalthat NPC1L1 plays an essential role in promoting intestinal cholesterol uptake via an ezetimibe-sensitive pathway. … [A33313] In genetically NPC1L1-deficient mice, a 70% reduction in intestinal cholesterol absorption was seen, and these mice were insensitive to ezetimibe treatment - it was determined based on these findings
Mixtures: EZETIMIBE E SIMVASTATINA EG, EZETIMIBE E SIMVASTATINA EGProducts: EZETIMIBE EGDexibuprofen
go.drugbank.com/drugs/DB09213ApprovedWithdrawnDexibuprofen has a slower dissolution rate in the simulated gastric and enteric juices compared with the racemic ibuprofen and displays improved oral bioavilability [A19259]. … It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties.
Products: Eu-Med 200 mg SchmerztablettenBrimonidine
go.drugbank.com/drugs/DB00484ApprovedInvestigationalBecause it is oxidately stable, brimonidine is associated with fewer reports of ocular allergic reactions compared to other alpha-2 adrenergic agonists. … in glaucoma.
Mixtures: BRIMONIDINA E TIMOLOLO EG, BRIMONIDINA E TIMOLOLO EGCategories: Sympathomimetics in Glaucoma TherapyTheophylline
go.drugbank.com/drugs/DB00277ApprovedInvestigationalA methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine recep...
Mixtures: Theophylline in Dextrose, Theophylline in DextroseProducts: Theo ER, Apo-theo ERHepatitis A Vaccine
go.drugbank.com/drugs/DB10989ApprovedInvestigational[A199185,L12756] In the US, the approved vaccine is inactivated while live Hepatitis A vaccines are currently available in other countries.[L13392]
Categories: Complex MixturesProducts: VAQTA 50 E/1 ml Injektionssuspension in einer Fertigspritze, VAQTA K pro infantibus 25 E/0,5 ml Injektionssuspension in einer FertigspritzeLovastatin
go.drugbank.com/drugs/DB00227ApprovedInvestigationalclinical studies to result in a 45.8% to 54.6% decrease in LDL cholesterol levels, while lovastatin has been found to have an average decrease in LDL-C of 25-40%. … [A181084] Elevated cholesterol levels, and in particular, elevated low-density lipoprotein (LDL) levels, are an important risk factor for the development of CVD.
Products: LOVASTATINA EGNepidermin
go.drugbank.com/drugs/DB14145InvestigationalMixtures: Easydew EX Repair Control Renewal Moisture, Easydew EX Repair Control Active Soothing SerumProducts: Easydew EX Repair Control Repair Control Egf, EASYDEW EX REPAIR CONTROL REPAIR CONTROL EGF 3mLAntihemophilic factor human
go.drugbank.com/drugs/DB13192ApprovedInvestigationalThe complex was developed by CSL Behring or Baxter Healthcare Corporation and approved in the 90s. … Factor VIII, but does not contain the B-domain, which has no known biological function and [DB11607], which is a fully recombinant factor VIII-Fc fusion protein which has an extended half-life compared
Mixtures: Wilate - von Willebrand Factor/Coagulation Factor VIII Complex (Human), von Willebrand Factor/Coagulation Factor VIII Complex (Human)Products: FACTANE 500 IU/5 ML IV ENJ ICIN LIYOFIZE TOZ ICEREN FLAKON, 1 ADET, FACTANE 1000 IU/10 ML IV ENJ ICIN LIYOFIZE TOZ ICEREN FLAKON, 1 ADETValaciclovir
go.drugbank.com/drugs/DB00577ApprovedInvestigationalIt was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline [L5671]. Valacyclovir is the L-valine ester of aciclovir. … Valaciclovir (valacyclovir), also known as _Valtrex_, is an antiviral drug that has been used to manage and treat various herpes infections for more than 2 decades.
Products: VALACICLOVIR EGAcorus calamus root
go.drugbank.com/drugs/DB14292InvestigationalAcorus calamus root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Products: derma MOBALNA EP 90 Hair Again Toner